Interesting Studies: Probably low carb related in one way or another
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Thank you.
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Low carb potentially an opioid alternative for osteoarthritis pain.
Related from last year:AlabasterVerve wrote: »Here's an interesting blog post by James Crownover worth reading: The Ketogenic Diet and Chronic pain
Take Home Points
1. Metabolic syndrome is associated with increased pain sensitivity
2. Caloric restriction, fasting, and the ketogenic diet have been shown reduce pain in animal models
3. A possible pathway for ketosis decreasing pain is by increasing adenosine
4. Another possible pathway is inhibition of the NLRP3 Inflammasome
5. The ketogenic diet may be an effective intervention to improve chronic pain
On a personal note, one of the reasons I still maintain a fairly strict low carb diet is because of this. I had no idea how bad I felt before low carb (6 months into eating proper food, exercising and losing 42lbs I thought I felt pretty great). But I was going through a large 150/200 count bottle of ibuprofen every single month - that was so normal for me I didn't realize how much pain I was experiencing. And I didn't notice the absence of that pain until I had three unopened bottles of ibuprofen stacked up because I kept buying it out of habit not noticing I didn't need it any more.
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I'm with you on that. I had easy carb food the other day and a chocolate bar when stuck at a hospital. I walked like a cripple. It took 3 days to improve.2
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Extended Ketogenic Diet and Physical Training Intervention in Military Personnel
Conclusions: US military personnel demonstrated high adherence to a KD and showed remarkable weight loss improvements in body composition, including loss of visceral fat, without compromising physical performance adaptations to exercise training. Implementation of a KD represents a credible strategy to enhance overall health and readiness of military service members who could benefit from weight loss and improved body composition.
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Science Daily: Neanderthals' main food source was definitely meat
Metro: Cavemen’s diet really did just consist of eating meat, researchers claim
new research has shown that actual cavemen ate meat and pretty much nothing else. Researchers analysed teeth left over from our ancestors and found out that they liked to snack out on things like reindeer and horse. And that’s about it. There were some occasional plants, of course. But mostly just other animals.
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Study first author Dr Jaouen said: ‘Using this technique, we discovered that the Neanderthal of Les Cottés had a purely terrestrial carnivore diet. She was not a late weaned child or a regular fish eater, and her people seem to have mostly hunted reindeers and horses. ‘We also confirmed that the Grotte du Renne Neandertal was a breastfeeding baby whose mother was a meat eater.’ Dr Michael Richards, of the Simon Fraser University in Canada, said: ‘Previous isotope results indicated a primarily carnivorous diet for Neanderthals, which matches the extensive archaeological record of animal remains found and deposited by Neanderthals. ‘There has recently been some frankly bizarre interpretations of the bulk isotope data ranging from Neanderthals primarily subsisting on aquatic plants to eating each other, both in direct contrast to the archaeological evidence.
Source: Exceptionally high δ15N values in collagen single amino acids confirm Neandertals as high-trophic level carnivores3 -
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Weight loss, improved physical performance, cognitive function, eating behavior, and metabolic profile in a 12-week ketogenic diet in obese adults.
The 12KD resulted in decreased appetite, significant weight loss of participants (-18 ± 9 kg men vs. -11 ± 3 kg women; P < .001), decreased emotional and external eating (P < .001 for both), increased body image satisfaction (P < .001) and improved physical performance (P < .001).
Biochemically, a significant drop in glucose (P = .026), and a significant increase in LDL-cholesterol (P = .031), CRP (P = .007), and BDNF (P = .035) were observed in the first 2 weeks; then, all listed parameters returned to baseline. On the other hand, a significant reduction in insulin (P < .001) and leptin levels (P < .001), and a significant increase in adiponectin (P = .008) and NPY (P = .009) were detected throughout the duration of the 12KD.
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Metabolic Abnormalities in Normal Weight Children Are Associated with Increased Visceral Fat Accumulation, Elevated Plasma Endotoxin Levels and a Higher Monosaccharide Intake.
In total, 45 normal weight children aged 5⁻9 years were included in the study, of whom nine suffered from metabolic abnormalities.
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Despite similar total calorie and macronutrient intake between groups, mean total fructose and total glucose intake (resulting mainly from sugar sweetened beverages, fruits and sweets) were higher in children with metabolic abnormalities than in healthy children. Time spent physically active was significantly higher in healthy normal weight children whereas time spent physically inactive was similar between groups. Furthermore, bacterial endotoxin levels were significantly higher in the peripheral plasma of normal weight children with metabolic abnormalities than in healthy normal weight children.
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Virta partners with the VA. "That’s it people: #Keto is now mainstream medical practice."
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Reversing Type 2 Diabetes: A Narrative Review of the Evidence
Evidence exists that T2D reversal is achievable using bariatric surgery, low-calorie diets (LCD), or carbohydrate restriction (LC).
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AlabasterVerve wrote: »Reversing Type 2 Diabetes: A Narrative Review of the Evidence
Evidence exists that T2D reversal is achievable using bariatric surgery, low-calorie diets (LCD), or carbohydrate restriction (LC).
Source
I wonder when the ADA will finally whole heartedly recommend lchf as the best diet for t2ds? Hopefully behind surgery or living on vlcd meal replacement shakes. yuck.1 -
AlabasterVerve wrote: »Reversing Type 2 Diabetes: A Narrative Review of the Evidence
Evidence exists that T2D reversal is achievable using bariatric surgery, low-calorie diets (LCD), or carbohydrate restriction (LC).
Source
I wonder when the ADA will finally whole heartedly recommend lchf as the best diet for t2ds? Hopefully behind surgery or living on vlcd meal replacement shakes. yuck.
It's about money not science - in my admittedly jaded opinion - so as soon as it's more profitable to recommend would be my guess... and we are surely reaching that tipping point given the VA is looking to trial keto to save money.
But will it matter? My guess is not a lot considering the ADA and similar are still to this day pushing out this BS and industries full on campaign to change the global food supply. It would be nice if at least government and non-profits (who should at least pretend to have peoples best interests at heart) stop actively harming the population though.1 -
Yikes. What was their simple recipe twist? Add more sugar?0
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Why would they recommend it when there is zero evidence that LCHF is the best diet for T2D?AlabasterVerve wrote: »Reversing Type 2 Diabetes: A Narrative Review of the Evidence
Evidence exists that T2D reversal is achievable using bariatric surgery, low-calorie diets (LCD), or carbohydrate restriction (LC).
Source
I wonder when the ADA will finally whole heartedly recommend lchf as the best diet for t2ds?
Yup, that's your only options when it comes to diabetes. How about weightloss, regardless of diet, and exercise.Hopefully behind surgery or living on vlcd meal replacement shakes. yuck.
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Umm, no. It's about evidence, and there is no evidence that LCHF is the best diet for T2D.AlabasterVerve wrote: »AlabasterVerve wrote: »Reversing Type 2 Diabetes: A Narrative Review of the Evidence
Evidence exists that T2D reversal is achievable using bariatric surgery, low-calorie diets (LCD), or carbohydrate restriction (LC).
Source
I wonder when the ADA will finally whole heartedly recommend lchf as the best diet for t2ds? Hopefully behind surgery or living on vlcd meal replacement shakes. yuck.
It's about money not science - in my admittedly jaded opinion - so as soon as it's more profitable to recommend would be my guess... and we are surely reaching that tipping point given the VA is looking to trial keto to save money.
So someone with diabetes can't enjoy a homeade scone? It's not like they are recommending a diet of only scones.But will it matter? My guess is not a lot considering the ADA and similar are still to this day pushing out this BS and industries full on campaign to change the global food supply. It would be nice if at least government and non-profits (who should at least pretend to have peoples best interests at heart) stop actively harming the population though.
Would love to see the evidence of your lovely little conspiracy theory you are pushing here that non-profits and the government are actively harming the population.
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Mysterious drug-resistant fungus is quietly sweeping the globe
Some scientists cite evidence that rampant use of fungicides on crops is contributing to the surge in drug-resistant fungi infecting humans.
Yet as the problem grows, it is little understood by the public — in part because the very existence of resistant infections is often cloaked in secrecy. With bacteria and fungi alike, hospitals and local governments are reluctant to disclose outbreaks for fear of being seen as infection hubs.0 -
"Restricting intake of foods high in added sugars as part of a low-sugar diet may increase their reinforcing value such that reducing consumption may be difficult to maintain."
Why coming back from indulgent holidays is a kitten.
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Conclusion LDL-C levels <70 mg/dL and low triglyceride levels were associated with increased risk of hemorrhagic stroke among women.
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Low Cholesterol Linked to Higher Risk of Bleeding Stroke in Women
The study involved 27,937 women age 45 and older enrolled in the Women’s Health Study who had total cholesterol, LDL cholesterol, high density lipoprotein (HDL) cholesterol, which is known as good cholesterol, and triglycerides measured at the start of the study. Researchers then reviewed medical records to determine how many women had a bleeding stroke.
With an average of 19 years of follow-up, researchers identified 137 women who had a bleeding stroke.
Nine out of 1,069 women with cholesterol 70 mg/dL or lower, or 0.8 percent, had a bleeding stroke, compared to 40 out of 10,067 women with cholesterol 100 mg/dL up to 130 mg/dL, or 0.4 percent. After adjusting for other factors that could affect risk of stroke, such as age, smoking status, high blood pressure and treatment with cholesterol-lowering medications, researchers found that those with very low LDL cholesterol were 2.2 times more likely to have a bleeding stroke.
For triglyceride levels, researchers divided the women into four groups. Women in the group with the lowest levels had fasting levels 74 mg/dL or lower, or non-fasting levels of 85 mg/dL or lower. Women in the group with the highest levels had fasting levels that were higher than 156 mg/dL, or non-fasting levels that were higher than 188 mg/dL.
Researchers found that 34 women of the 5,714 women with the lowest levels of triglycerides, or 0.6 percent, had a bleeding stroke, compared to 29 women of the 7,989 with the highest triglycerides, or 0.4 percent. After adjusting for other factors that could affect risk, researchers found that those with the lowest triglycerides were twice as likely to have a bleeding stroke.
No difference in risk was found for total cholesterol or HDL cholesterol.0 -
Re: Nephropathy in dietary hyperoxaluria: A potentially preventable acute or chronic kidney disease
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Low carb and mainstream nutrition:
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Re: Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet
Conclusions
Switching to the KD was associated with increased cholesterol and inflammatory markers, decreased triglycerides, and decreased insulin‐mediated antilipolysis. Glucose homeostasis parameters were diet dependent and test meal dependent.
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