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Gut Microbiome impact on Health and Fitness
Replies
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GaleHawkins wrote: »Autism symptoms reduced nearly 50 percent two years after fecal transplant
https://sciencedaily.com/releases/2019/04/190409093725.htm
"In a new study, "Long-term benefit of Microbiota Transfer Therapy in Autism Symptoms and Gut Microbiota," published in Scientific Reports, Arizona State University researchers Rosa Krajmalnik-Brown, Ph.D., James Adams, Ph.D, and lead author Dae-Wook Kang, Ph.D, demonstrate long-term beneficial effects for children diagnosed with ASD through a revolutionary technique known as Microbiota Transfer Therapy (MTT), a special type of fecal transplant originally pioneered by Dr. Thomas Borody, an Australian gastroenterologist. Remarkably, improvements in gut health and autism symptoms appear to persist long after treatment.
At two years post-treatment, most of the initial improvements in gut symptoms remained. In addition, parents reported a slow steady reduction of ASD symptoms during treatment and over the next two years. A professional evaluator found a 45% reduction in core ASD symptoms (language, social interaction and behavior) at two years post-treatment compared to before treatment began.
"We are finding a very strong connection between the microbes that live in our intestines and signals that travel to the brain," said Krajmalnik-Brown, a professor at the Biodesign Swette Center for Environmental Biotechnology at the Biodesign Institute and ASU's School for Sustainable Engineering and the Built Environment. "Two years later, the children are doing even better, which is amazing."
"Many kids with autism have gastrointestinal problems, and some studies, including ours, have found that those children also have worse autism-related symptoms," said Krajmalnik-Brown. "In many cases, when you are able to treat those gastrointestinal problems, their behavior improves."
Roughly 30-50% of all people with autism have chronic gastrointestinal (GI) problems, primarily constipation and/or diarrhea that can last for many years. That chronic discomfort and pain can cause irritability, decreased attention and learning, and negatively impact behavior.
An earlier study with only vancomycin (an antibiotic) had found major temporary improvements in GI and autism symptoms, but the benefits were lost a few weeks after treatment stopped despite use of over-the-counter probiotics.
So, the question at hand was what's going on in the gut, and how does it affect both physical and behavioral symptoms of autism, and how can we develop a long-lasting treatment?
Krajmalnik-Brown, Kang and Adams have shown that by transferring healthy microbiota to individuals lacking certain gut bacteria, it is possible to "donate" a more diverse set of bacteria into the patient and improve gut health.
In Australia, Fecal Microbiota Transplantation (FMT) was initially developed by Borody. At his Centre for Digestive Diseases in Sydney, Borody has overseen more than 18,000 FMTs for various disorders since 1987. He pioneered in Australia the use of FMT for colitis and Clostridium difficile infection, and was the first to use oral FMT to treat children with ASD. Only one dose of FMT is usually enough to cure C. Difficile infections, but his patients with autism were far harder to treat. He discovered that three months of daily FMT was required to treat his autism patients, but eventually resulted in significant improvements in both GI and autism symptoms.
Based on his experience with his patients, Borody led the design of the clinical treatment used at ASU for this study....."
CHILD’S RISK OF AUTISM CAN CHANGE BASED ON HEALTH OF MOTHER’S GUT
https://newsweek.com/autism-gut-health-signs-prevention-pregnancy-women-1031661
"New research suggests that the risk of developing autism is determined by the mother’s gut during pregnancy.
Scientists at the University of Virginia School of Medicine were able to analyze pregnant women’s microbiomes to determine the child’s risk of developing autism. The study, published July 2 in The Journal of Immunology, also researched how to use this finding to halt the development of autism-like neurodevelopmental disorders in mice.
“Our study was interested in understanding how the microbiome, which is the community of microbes that live within our gut, can shift susceptibility to autism-spectrum disorder,” John Lukens, assistant professor at the University of Virginia and lead author on the study, told Newsweek. To do this, the team studied, in part, interleukin-17a.
“It’s kind of the middleman between the gut and the brain,” Lukens says. Scientists at the Massachusetts Institute of Technology found that the inflammatory molecule interleukin-17a, or IL-17a, can influence the development of autism-like disorders in the brain. IL-17a has also been found to influence the development of multiple sclerosis and rheumatoid arthritis.
“What it can do during pregnancy is alter how the brain is developed and wired,” Lukens explains..... "
As someone who is autistic I'm going to call you out.
There are no such thing as autism "symptoms", because autism in NOT A DISEASE, it is a neurological condition, our brains are wired a little differently to a neurotypical and no 2 people with autism are the same or have the same issues with the nt world. We are not ill and no treatment is going to cure us. We do learn to a greater or lesser degree to fit a little better in to your world, but having someone else's cr@p stuck up my bum is not going to magically re-wire my brain and to be honest I wouldn't want it to.
Amen!
My son is on the spectrum and although there are days my heart breaks for him due to how cruel the world can be I would not change him for anything.19 -
GaleHawkins wrote: »nutmegoreo wrote: »GaleHawkins wrote: »https://gizmodo.com/fecal-transplant-patient-killed-by-superbug-traced-to-d-1835521476
Fecal Transplant Patient Killed by Superbug Traced to Donor Stool
" “FDA is informing members of the medical and scientific communities and other interested persons of the potential risk of transmission of [multidrug-resistant organisms] by FMT and the resultant serious adverse reactions that may occur,” the agency said in its safety communication.
It’s likely that the pre-existing health of both patients contributed to the severity of their illnesses, since both had weakened immune systems. But the infections could have been prevented had doctors in the trial been looking for these bacteria in donors to begin with, the FDA said.
In 2013, as FMT trials began taking off, the agency announced it would take a hands-off approach in regulating its early use for C. diff infections (generally, any new drug or treatment for a disease needs to go through a lengthy FDA approval process before it can be widely available). So long as patients were told upfront about the potential risks and experimental nature of the treatment by doctors, it would be less strict in approving or supervising new clinical trials. But as a result of these tragic cases, the agency is now demanding that all investigational trials preemptively screen their donors for risk factors that would make them more likely to have superbugs, as well as to test their donor samples for these bacteria. Doctors should tell their volunteers beforehand about these now-discovered serious risks, too. "
Hmmm..... the risks of just blindly following every new thing before the science has been hashed out.
True but some trust their health decisions to healthcare professionals without vetting their advice. It has long been known compromised immune systems puts one at a higher risk of premature death from disease. We know FMT is awesome for some but it is important to know the quality of it as if it was a drug.
Changing the gut microbiome in the positive direction by diet alone seems to be the first step to try. I expect that is the reason Keto has worked so well for me since 2014. I can grasp the ideas behind FMT but why do it when there are more natural ways like changing the source of one calories and that will never be the same for everyone.
FMT for autism sounds very promising for kids.
I agree that questioning medical professionals is important. Anyone who receives health treatment for any medical condition should ask questions, take notes, and keep track of what is going on. It's wise for patients to be their own advocates. This is not the same thing as assuming anything that has a single study showing some benefit for new treatments as being the be all end off for new treatments. The science is interesting, but it's in its infancy. Along with so many other things that are still being researched. Medical practice can take a long time to change, partly because so many new treatments will have unknown side effects that can be detrimental. Keeping open to new science is great, but assuming it is infallible is a mistake, IMO.11 -
@firef1y72 I agree autism is not a disease but is in the USA considered a Disorder with varying levels from person to person. I do not think anyone is looking to cure autism since we are not sure what causes the disorder in the first place. There are some hints of preventing new cases of autism down the road perhaps. The FMT I think is only about 10 years in development for humans.
The Smithsonian Magazine had an article on autism last week called How the Gut Microbiome Could Provide a New Tool to Treat Autism and some video from the researchers.
https://smithsonianmag.com/science-nature/how-gut-microbiome-could-provide-new-tool-treat-autism-180972416/13 -
The funny thing about fecal transplant is the labs that process it use people who have super healthy poop. They are paid for their contributions so they are literally paid poopers😄5
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SeptemberFeyre wrote: »The funny thing about fecal transplant is the labs that process it use people who have super healthy poop. They are paid for their contributions so they are literally paid poopers😄
Yeah, not much any different from blood, plasma/immunoglobulin, semen, etc. donations...most disgusting part is when reading about doing a test dose (for per oral route at least) of fecal transplant capsules & monitoring gag reflex...not to mention how it is collected, stored, & prepared for use...🤮🤮🤮
Note: some recent setbacks recently with a few deaths post fecal transplant donation in the news...infancy indeed2 -
Keto_Vampire wrote:Yeah, not much any different from blood, plasma/immunoglobulin, semen, etc. donations...most disgusting part is when reading about doing a test dose (for per oral route at least) of fecal transplant capsules & monitoring gag reflex...not to mention how it is collected, stored, & prepared for use...🤮🤮🤮
Note: some recent setbacks recently with a few deaths post fecal transplant donation in the news...infancy indeed
Eww! I’ve never heard of ingesting it orally. What I did learn is it is somehow sterilized. I’m not sure how they do that and keep all the good bacteria alive, but they manage somehow.0 -
GaleHawkins wrote: »@firef1y72 I agree autism is not a disease but is in the USA considered a Disorder with varying levels from person to person. I do not think anyone is looking to cure autism since we are not sure what causes the disorder in the first place. There are some hints of preventing new cases of autism down the road perhaps. The FMT I think is only about 10 years in development for humans.
The Smithsonian Magazine had an article on autism last week called How the Gut Microbiome Could Provide a New Tool to Treat Autism and some video from the researchers.
https://smithsonianmag.com/science-nature/how-gut-microbiome-could-provide-new-tool-treat-autism-180972416/
I do disagree with this statement - there's a huge industry devoted to scamming parents who are desperate to find some treatment that will cure (or prevent) autism.6 -
GaleHawkins wrote: »Autism symptoms reduced nearly 50 percent two years after fecal transplant
https://sciencedaily.com/releases/2019/04/190409093725.htm
"In a new study, "Long-term benefit of Microbiota Transfer Therapy in Autism Symptoms and Gut Microbiota," published in Scientific Reports, Arizona State University researchers Rosa Krajmalnik-Brown, Ph.D., James Adams, Ph.D, and lead author Dae-Wook Kang, Ph.D, demonstrate long-term beneficial effects for children diagnosed with ASD through a revolutionary technique known as Microbiota Transfer Therapy (MTT), a special type of fecal transplant originally pioneered by Dr. Thomas Borody, an Australian gastroenterologist. Remarkably, improvements in gut health and autism symptoms appear to persist long after treatment.
At two years post-treatment, most of the initial improvements in gut symptoms remained. In addition, parents reported a slow steady reduction of ASD symptoms during treatment and over the next two years. A professional evaluator found a 45% reduction in core ASD symptoms (language, social interaction and behavior) at two years post-treatment compared to before treatment began.
"We are finding a very strong connection between the microbes that live in our intestines and signals that travel to the brain," said Krajmalnik-Brown, a professor at the Biodesign Swette Center for Environmental Biotechnology at the Biodesign Institute and ASU's School for Sustainable Engineering and the Built Environment. "Two years later, the children are doing even better, which is amazing."
"Many kids with autism have gastrointestinal problems, and some studies, including ours, have found that those children also have worse autism-related symptoms," said Krajmalnik-Brown. "In many cases, when you are able to treat those gastrointestinal problems, their behavior improves."
Roughly 30-50% of all people with autism have chronic gastrointestinal (GI) problems, primarily constipation and/or diarrhea that can last for many years. That chronic discomfort and pain can cause irritability, decreased attention and learning, and negatively impact behavior.
An earlier study with only vancomycin (an antibiotic) had found major temporary improvements in GI and autism symptoms, but the benefits were lost a few weeks after treatment stopped despite use of over-the-counter probiotics.
So, the question at hand was what's going on in the gut, and how does it affect both physical and behavioral symptoms of autism, and how can we develop a long-lasting treatment?
Krajmalnik-Brown, Kang and Adams have shown that by transferring healthy microbiota to individuals lacking certain gut bacteria, it is possible to "donate" a more diverse set of bacteria into the patient and improve gut health.
In Australia, Fecal Microbiota Transplantation (FMT) was initially developed by Borody. At his Centre for Digestive Diseases in Sydney, Borody has overseen more than 18,000 FMTs for various disorders since 1987. He pioneered in Australia the use of FMT for colitis and Clostridium difficile infection, and was the first to use oral FMT to treat children with ASD. Only one dose of FMT is usually enough to cure C. Difficile infections, but his patients with autism were far harder to treat. He discovered that three months of daily FMT was required to treat his autism patients, but eventually resulted in significant improvements in both GI and autism symptoms.
Based on his experience with his patients, Borody led the design of the clinical treatment used at ASU for this study....."
CHILD’S RISK OF AUTISM CAN CHANGE BASED ON HEALTH OF MOTHER’S GUT
https://newsweek.com/autism-gut-health-signs-prevention-pregnancy-women-1031661
"New research suggests that the risk of developing autism is determined by the mother’s gut during pregnancy.
Scientists at the University of Virginia School of Medicine were able to analyze pregnant women’s microbiomes to determine the child’s risk of developing autism. The study, published July 2 in The Journal of Immunology, also researched how to use this finding to halt the development of autism-like neurodevelopmental disorders in mice.
“Our study was interested in understanding how the microbiome, which is the community of microbes that live within our gut, can shift susceptibility to autism-spectrum disorder,” John Lukens, assistant professor at the University of Virginia and lead author on the study, told Newsweek. To do this, the team studied, in part, interleukin-17a.
“It’s kind of the middleman between the gut and the brain,” Lukens says. Scientists at the Massachusetts Institute of Technology found that the inflammatory molecule interleukin-17a, or IL-17a, can influence the development of autism-like disorders in the brain. IL-17a has also been found to influence the development of multiple sclerosis and rheumatoid arthritis.
“What it can do during pregnancy is alter how the brain is developed and wired,” Lukens explains..... "
As someone who is autistic I'm going to call you out.
There are no such thing as autism "symptoms", because autism in NOT A DISEASE, it is a neurological condition, our brains are wired a little differently to a neurotypical and no 2 people with autism are the same or have the same issues with the nt world. We are not ill and no treatment is going to cure us. We do learn to a greater or lesser degree to fit a little better in to your world, but having someone else's cr@p stuck up my bum is not going to magically re-wire my brain and to be honest I wouldn't want it to.
Autism does have symptoms in the sense that a diagnosis is made based on observations of behaviors, not a neurological exam. A fecal transplant is not intended as a cure or fix for autism, the idea is that by changing the gut microbiome, it can impact some of the symptoms (again, the observed behaviors that brought about the diagnosis) and lessen them to some extent. ABA therapy isn't going to "cure" a child with autism, but it can help them learn to manage the symptoms/observable behaviors. The research is just trying to see if there is a medical approach that can accomplish something along those lines.
It's more like using medication to treat anxiety or ADHD (also neurological conditions which doesn't mean a person is ill) - it doesn't cure anything but can allow someone to manage the symptoms more effectively. For people who are interested in the treatment, it could one day be a promising option.9 -
As the OP I wanted to share an article that is one take on how to read scientific research papers without being a scientific researcher. The subject of the gut microbiome impact on health and fitness has been going on in labs for a long time but government funding for this type of research did not get underway in a major way until about a decade ago it seems.
https://thenextweb.com/basics/2019/06/14/how-to-read-a-scientific-research-paper/
Tracking the funding is sometimes the most important I find personally. Money is often the main driver of everything where we want to except it or not. Every organization talks about money where it be our kids sport team, religion or research especially if it is medically related.
Getting funded is the first step to most all medical research.
The quality of the research team is always going to be a factor but medical breakthroughs like in other areas often come through Skunk Works types groups.
https://searchcio.techtarget.com/definition/skunkworks
The gut microbiome impacts all readers but the big question I have today is the how and why as in the article link below.
https://nature.com/articles/d41586-019-01851-x
17 JUNE 2019
Microbes make metabolic mischief by targeting drugs
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
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GaleHawkins wrote: »As the OP I wanted to share an article that is one take on how to read scientific research papers without being a scientific researcher. The subject of the gut microbiome impact on health and fitness has been going on in labs for a long time but government funding for this type of research did not get underway in a major way until about a decade ago it seems.
https://thenextweb.com/basics/2019/06/14/how-to-read-a-scientific-research-paper/
Tracking the funding is sometimes the most important I find personally. Money is often the main driver of everything where we want to except it or not. Every organization talks about money where it be our kids sport team, religion or research especially if it is medically related.
Getting funded is the first step to most all medical research.
The quality of the research team is always going to be a factor but medical breakthroughs like in other areas often come through Skunk Works types groups.
https://searchcio.techtarget.com/definition/skunkworks
The gut microbiome impacts all readers but the big question I have today is the how and why as in the article link below.
https://nature.com/articles/d41586-019-01851-x
17 JUNE 2019
Microbes make metabolic mischief by targeting drugs
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
If only that were true.11 -
GaleHawkins wrote: »
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
Isn't that like calibrating an instrument according to a faulty standard?
While I feel like this topic is a promising area of research, what you describe as "keeping an open mind" seems more akin to gullibility. While we may not need concrete evidence for every health choice we make, I wouldn't want to make changes based on every hypothesis that comes along.11 -
GaleHawkins wrote: »
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
Isn't that like calibrating an instrument according to a faulty standard?
While I feel like this topic is a promising area of research, what you describe as "keeping an open mind" seems more akin to gullibility. While we may not need concrete evidence for every health choice we make, I wouldn't want to make changes based on every hypothesis that comes along.
In my case to I just shifted my calorie sources when shopping at Walmart and Krogers to enhance my health so there is no need to dive in the deep end of the pool is one is going swimming for the first time.
I just wanted to know how eating low carb in my case for the past 5 years has fixed or improved 40 years of serious health issues. Understanding cravings can come from one's own gut microbiome was exciting news in my seeking the WHY. That covers why Willpower is not a factor in weight loss often.11 -
GaleHawkins wrote: »As the OP I wanted to share an article that is one take on how to read scientific research papers without being a scientific researcher. The subject of the gut microbiome impact on health and fitness has been going on in labs for a long time but government funding for this type of research did not get underway in a major way until about a decade ago it seems.
https://thenextweb.com/basics/2019/06/14/how-to-read-a-scientific-research-paper/
Tracking the funding is sometimes the most important I find personally. Money is often the main driver of everything where we want to except it or not. Every organization talks about money where it be our kids sport team, religion or research especially if it is medically related.
Getting funded is the first step to most all medical research.
The quality of the research team is always going to be a factor but medical breakthroughs like in other areas often come through Skunk Works types groups.
https://searchcio.techtarget.com/definition/skunkworks
The gut microbiome impacts all readers but the big question I have today is the how and why as in the article link below.
https://nature.com/articles/d41586-019-01851-x
17 JUNE 2019
Microbes make metabolic mischief by targeting drugs
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
Two of the many problems with this post, is that you a. rarely post peer reviewed journal articles and b. when you do, they're frequently not open access. While you might have access to them, I have my doubts given that when I asked you if you knew what a references section was, you weren't able to give me a correct answer.
Do I think it's important to know how to make one's way through journal articles? Yes. I don't think the link you posted was an especially good explanation though and it's kind of moot given that you so rarely post those sorts of articles. I don't like that so many of the documents in this are word files as opposed to PDFs, but this website from UC Merced would be good for you specifically. Note the "Scholarly vs. Serious" section. Most of what you link to falls into the "serious" box, though some also fall into the "popular" category. Very few of the articles you post are actually scholarly.11 -
GaleHawkins wrote: »As the OP I wanted to share an article that is one take on how to read scientific research papers without being a scientific researcher. The subject of the gut microbiome impact on health and fitness has been going on in labs for a long time but government funding for this type of research did not get underway in a major way until about a decade ago it seems.
https://thenextweb.com/basics/2019/06/14/how-to-read-a-scientific-research-paper/
Tracking the funding is sometimes the most important I find personally. Money is often the main driver of everything where we want to except it or not. Every organization talks about money where it be our kids sport team, religion or research especially if it is medically related.
Getting funded is the first step to most all medical research.
The quality of the research team is always going to be a factor but medical breakthroughs like in other areas often come through Skunk Works types groups.
https://searchcio.techtarget.com/definition/skunkworks
The gut microbiome impacts all readers but the big question I have today is the how and why as in the article link below.
https://nature.com/articles/d41586-019-01851-x
17 JUNE 2019
Microbes make metabolic mischief by targeting drugs
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
Once again it's abundantly clear that you completely misunderstand (or disregard) the links you're posting5 -
GaleHawkins wrote: »As the OP I wanted to share an article that is one take on how to read scientific research papers without being a scientific researcher. The subject of the gut microbiome impact on health and fitness has been going on in labs for a long time but government funding for this type of research did not get underway in a major way until about a decade ago it seems.
https://thenextweb.com/basics/2019/06/14/how-to-read-a-scientific-research-paper/
Tracking the funding is sometimes the most important I find personally. Money is often the main driver of everything where we want to except it or not. Every organization talks about money where it be our kids sport team, religion or research especially if it is medically related.
Getting funded is the first step to most all medical research.
The quality of the research team is always going to be a factor but medical breakthroughs like in other areas often come through Skunk Works types groups.
https://searchcio.techtarget.com/definition/skunkworks
The gut microbiome impacts all readers but the big question I have today is the how and why as in the article link below.
https://nature.com/articles/d41586-019-01851-x
17 JUNE 2019
Microbes make metabolic mischief by targeting drugs
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
The brain does not work like this. We continually reference all data from a state of confirmational bias. Unless one follows a strict process of objective rationalization what you perceive as a "BS detector" is much closer to an "ego protector". Hence why most people shut down, break off conversations, and respond emotionally when confronted with conflicting data. Only a very small percentage of the population has the courage to question "what is known".
The fallacy in this is that a final answer could exist.7 -
The brain does not work like this. We continually reference all data from a state of confirmational bias. Unless one follows a strict process of objective rationalization what you perceive as a "BS detector" is much closer to an "ego protector". Hence why most people shut down, break off conversations, and respond emotionally when confronted with conflicting data. Only a very small percentage of the population has the courage to question "what is known".
The fallacy in this is that a final answer could exist.
QFT.
I've seen this in practice on many occasions. For example, I know someone who is currently studying an MSc in Environment Science, and is a climate change skeptic. He constantly questions any evidence of climate change that is presented to him - but will implicitly trust any source that says that climate change is a lie. He once offered in evidence a website that claimed that climate change was an alien conspiracy. No lie.2 -
The brain does not work like this. We continually reference all data from a state of confirmational bias. Unless one follows a strict process of objective rationalization what you perceive as a "BS detector" is much closer to an "ego protector". Hence why most people shut down, break off conversations, and respond emotionally when confronted with conflicting data. Only a very small percentage of the population has the courage to question "what is known".
The fallacy in this is that a final answer could exist.
13 -
The brain does not work like this. We continually reference all data from a state of confirmational bias. Unless one follows a strict process of objective rationalization what you perceive as a "BS detector" is much closer to an "ego protector". Hence why most people shut down, break off conversations, and respond emotionally when confronted with conflicting data. Only a very small percentage of the population has the courage to question "what is known".
The fallacy in this is that a final answer could exist.
QFT.
I've seen this in practice on many occasions. For example, I know someone who is currently studying an MSc in Environment Science, and is a climate change skeptic. He constantly questions any evidence of climate change that is presented to him - but will implicitly trust any source that says that climate change is a lie. He once offered in evidence a website that claimed that climate change was an alien conspiracy. No lie.
Even using the words - skeptic, denier, believer, etc. expose an individual bias.
Objective evidence only works when you properly state parameters, design of experiment, and proposed outcome. If you don't even begin by stating an ideal then your design is sorely lacking.
Pertaining to this thread - What is the ideal gut microbiome?
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The brain does not work like this. We continually reference all data from a state of confirmational bias. Unless one follows a strict process of objective rationalization what you perceive as a "BS detector" is much closer to an "ego protector". Hence why most people shut down, break off conversations, and respond emotionally when confronted with conflicting data. Only a very small percentage of the population has the courage to question "what is known".
The fallacy in this is that a final answer could exist.
QFT.
I've seen this in practice on many occasions. For example, I know someone who is currently studying an MSc in Environment Science, and is a climate change skeptic. He constantly questions any evidence of climate change that is presented to him - but will implicitly trust any source that says that climate change is a lie. He once offered in evidence a website that claimed that climate change was an alien conspiracy. No lie.
What is the ideal gut microbiome?
I'm hoping that it's Taco based.
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GaleHawkins wrote: »GaleHawkins wrote: »
One thing I try to keep in my mind is research is not the final answer because our understanding of gut microbiome impact on health and fitness will continue to evolve so an open mind is required for my own health and fitness.
Since no one has the final answer on the subject I will work to read and understand each research paper I can find on the subject regardless of the authors stated or unstated objectives.
As the author of this paper about reading research papers points out the more we read on any subject the better our BS detector works.
Isn't that like calibrating an instrument according to a faulty standard?
While I feel like this topic is a promising area of research, what you describe as "keeping an open mind" seems more akin to gullibility. While we may not need concrete evidence for every health choice we make, I wouldn't want to make changes based on every hypothesis that comes along.
In my case to I just shifted my calorie sources when shopping at Walmart and Krogers to enhance my health so there is no need to dive in the deep end of the pool is one is going swimming for the first time.
I just wanted to know how eating low carb in my case for the past 5 years has fixed or improved 40 years of serious health issues. Understanding cravings can come from one's own gut microbiome was exciting news in my seeking the WHY. That covers why Willpower is not a factor in weight loss often.
As has been pointed out to you time and again, you do not know, and cannot possibly know, if the health improvements you realize were from the change to low carb or the weight loss itself. Now you want to throw gut biome into the mix as a possible source?
When you hear hoofbeats, why look for unicorns or zebras rather than horses?14
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