Why Aspartame Isn't Scary
Replies
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queenliz99 wrote: »crzycatlady1 wrote: »Overall, I agree with the original explanation of very little to no proof that aspartame causes cancer. There are far worse things around us that are making people sick.
That is not my worry about it. What I think this article is missing is a big point that aspartame affects insulin levels as much as sugar, and causes people to easily overeat and consume way more than needed. In other words, it is a perfect tool to help you gain weigth.
Of course, I'm not talking here about occasional can of Diet Coke here and there, but consumption of 2-3 cans per day or more.
There are numerous studies that clearly talk about this well-researched effect.
You can even look around yourself and see connection between overconsumption and Diet drinks. I've seen people eating 2000+ calories meal and feeling being on diet just by the fact that Diet Coke is next to them.....
Where to even start?
1. I used to be overweight and a pre-diabetic. Decided to lose the weight and one of the first things I did was switch from regular soda, to diet. Before that I did not consume artificial sweeteners.
2. Lost 50lbs, while drinking 4-6 cans of diet soda a day
3. Blood work improved drastically, glucose numbers started coming back under 100
4. I've been maintaining the loss for several years now:
-I still drink 4-5 cans of diet soda a day
-my glucose numbers are still consistently under 100
-rest of my blood work is also consistently good
-blood pressure is great
-latest waist measurement was 25 (done by a medical professional)
-my bmi is 21.
5. Diet soda does not cause me to overeat on calories and I have no problem maintaining my loss while continuing to drink diet soda every single day.
So yeah, I must be a special freak snowflake
Freak!
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brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Just to be clear, i would have to drink 3200mg of aspatame. Considering there is about 180mg in a can of diet coke, i would have to drink about 17 cans a day (this is at 40mg/kg of body weight as done by the study).
Soo...... i think i am good.6 -
brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Just to be clear, i would have to drink 3200mg of aspatame. Considering there is about 180mg in a can of diet coke, i would have to drink about 17 cans a day (this is at 40mg/kg of body weight as done by the study).
Soo...... i think i am good.
they chose the amount specifically because the FDA says that amount is safe. Yet the study proves that this amount in fact is not safe. The study was only for 90 days, if lower rates of aspartame simply cause a lower rate of damage then if youre looking at a lifetime of consuming it, you will still have more neuron death than the rats did in this study. If youre looking at 1 can of diet coke a day then you could say 90 days x 17 = 4 years for you to get to the same amount of neuron death as the rats in the study suffered in 90 days. Also, the neuron death was very significant, even a fraction of that would be bad. So I dont think anyone is good when they are eating aspartame. But that's just my advice to you.
Its also proof that it is a carcinogen, as it showed that free radicals were increased due to the aspartame.
I've had personal experience with someone who drank around 8 cans of diet coke a day for 10 years and yes her memory was very bad and the addiction was very real. I do not think it's just a coincidence that she happened to have memory problems when aspartame is proven to damage the hippocampus.
Argue that you think it's really safe if you want and keep on drinking it, I dont mind. But I wouldnt drink it. There are a lot more studies out there if you want to read up on it, I just chose that one at random really because it looked well done. It's your life anyway.3 -
diannethegeek wrote: »This thread.
I know, right? - 30 pages of people debunking myths, giving scientific information etc - and then along pops yet another newbie posting 1 person I know who drank diet soda got cancer, brain holes, self combusted, whatever, and my woo page proves it - and back to beginning of circle......
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brentfostwood904 wrote: »brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Just to be clear, i would have to drink 3200mg of aspatame. Considering there is about 180mg in a can of diet coke, i would have to drink about 17 cans a day (this is at 40mg/kg of body weight as done by the study).
Soo...... i think i am good.
they chose the amount specifically because the FDA says that amount is safe. Yet the study proves that this amount in fact is not safe. The study was only for 90 days, if lower rates of aspartame simply cause a lower rate of damage then if youre looking at a lifetime of consuming it, you will still have more neuron death than the rats did in this study. If youre looking at 1 can of diet coke a day then you could say 90 days x 17 = 4 years for you to get to the same amount of neuron death as the rats in the study suffered in 90 days. Also, the neuron death was very significant, even a fraction of that would be bad. So I dont think anyone is good when they are eating aspartame. But that's just my advice to you.
Its also proof that it is a carcinogen, as it showed that free radicals were increased due to the aspartame.
I've had personal experience with someone who drank around 8 cans of diet coke a day for 10 years and yes her memory was very bad and the addiction was very real. I do not think it's just a coincidence that she happened to have memory problems when aspartame is proven to damage the hippocampus.
Argue that you think it's really safe if you want and keep on drinking it, I dont mind. But I wouldnt drink it. There are a lot more studies out there if you want to read up on it, I just chose that one at random really because it looked well done. It's your life anyway.
None of this has even shown to translate into humans. Also, context and dosage apply. Rats taking in their body weight in aspartame is bad. You cannot state the same for normal amounts of aspartame. It doesn't work like that. You would have to test rats at normal intake levels. Heck, even water has toxic levels. And just because it has toxic levels doesn't mean you can generalize it and say all levels of water are toxic. Do you know that apples contain cyanide?
7 -
Ah, but that apple Snow White ate was really full of it, so no one should eat apples.7
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brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
For your reading pleasure:
http://seriecientifica.org/sites/default/files/scl_enc_butchko.pdf
http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2013.EN-399/pdf1 -
Sorry but you don't get to decide what is "scary" to others.1
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ThatUserNameIsAllReadyTaken wrote: »Sorry but you don't get to decide what is "scary" to others.
You're allowed to be scared by zombies, we can tell you why that's silly.13 -
brentfostwood904 wrote: »brentfostwood904 wrote: »aspartame overexcites neurons in the brain, causing them to die, in specific areas such as the hippocampus. Animal studies with aspartame have shown a hole in the hippocampus being caused by aspartame. My ex girlfriend who is now 21 used to drink about 8 cans of diet coke every day for years since the age of 12, and her memory is terrible, I fully believe the link to neuron death due to aspartame and I've seen how addictive it can get (she could not deal with not having diet coke at all and any aspartame free substitute did not work). It is something which is both addictive and causes death of neurons. Best avoided.
Do you have a source for this claim?
go and check out the animal model studies on aspartame and the hippocampus, theres a lot more than one out there. Read the long term studies because a lot of the short term studies say there is no effect.. but they are done over a stupid amount of time like 2 days.. so these ones are hardly well designed studies.
The studies that implicate aspartame causing problems in animals use such ridiculous quantities of aspartame that you'd have to drink thousands of gallons of diet soda per day in order to get a comparable amount in your diet.
Even if humans would suffer the same side effects that the mice did in these studies (which we don't even know that we would), if you drink enough diet soda to attain sufficient aspartame to see those side effects, you would die the first day due to over-hydration flushing your body of electrolytes.3 -
Carlos_421 wrote: »brentfostwood904 wrote: »brentfostwood904 wrote: »aspartame overexcites neurons in the brain, causing them to die, in specific areas such as the hippocampus. Animal studies with aspartame have shown a hole in the hippocampus being caused by aspartame. My ex girlfriend who is now 21 used to drink about 8 cans of diet coke every day for years since the age of 12, and her memory is terrible, I fully believe the link to neuron death due to aspartame and I've seen how addictive it can get (she could not deal with not having diet coke at all and any aspartame free substitute did not work). It is something which is both addictive and causes death of neurons. Best avoided.
Do you have a source for this claim?
go and check out the animal model studies on aspartame and the hippocampus, theres a lot more than one out there. Read the long term studies because a lot of the short term studies say there is no effect.. but they are done over a stupid amount of time like 2 days.. so these ones are hardly well designed studies.
The studies that implicate aspartame causing problems in animals use such ridiculous quantities of aspartame that you'd have to drink thousands of gallons of diet soda per day in order to get a comparable amount in your diet.
Even if humans would suffer the same side effects that the mice did in these studies (which we don't even know that we would), if you drink enough diet soda to attain sufficient aspartame to see those side effects, you would die the first day due to over-hydration flushing your body of electrolytes.
Whoa, dude! Stop it with your common sense;)5 -
ThatUserNameIsAllReadyTaken wrote: »Sorry but you don't get to decide what is "scary" to others.
But he does have the right to share valuable information regarding the reasons why there is nothing to fear.5 -
jillybeansalad wrote: »"real," "processed," "fake," "natural," etc
I wish we could all agree on what these even mean.
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
1 -
GottaBurnEmAll wrote: »
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
1 -
Overall, I agree with the original explanation of very little to no proof that aspartame causes cancer. There are far worse things around us that are making people sick.
That is not my worry about it. What I think this article is missing is a big point that aspartame affects insulin levels as much as sugar, and causes people to easily overeat and consume way more than needed. In other words, it is a perfect tool to help you gain weigth.
Of course, I'm not talking here about occasional can of Diet Coke here and there, but consumption of 2-3 cans per day or more.
There are numerous studies that clearly talk about this well-researched effect.
You can even look around yourself and see connection between overconsumption and Diet drinks. I've seen people eating 2000+ calories meal and feeling being on diet just by the fact that Diet Coke is next to them.....
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
5 -
Overall, I agree with the original explanation of very little to no proof that aspartame causes cancer. There are far worse things around us that are making people sick.
That is not my worry about it. What I think this article is missing is a big point that aspartame affects insulin levels as much as sugar, and causes people to easily overeat and consume way more than needed. In other words, it is a perfect tool to help you gain weigth.
Of course, I'm not talking here about occasional can of Diet Coke here and there, but consumption of 2-3 cans per day or more.
There are numerous studies that clearly talk about this well-researched effect.
You can even look around yourself and see connection between overconsumption and Diet drinks. I've seen people eating 2000+ calories meal and feeling being on diet just by the fact that Diet Coke is next to them.....
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
Also diet coke is the drink of choice for many anorexics0 -
singingflutelady wrote: »Overall, I agree with the original explanation of very little to no proof that aspartame causes cancer. There are far worse things around us that are making people sick.
That is not my worry about it. What I think this article is missing is a big point that aspartame affects insulin levels as much as sugar, and causes people to easily overeat and consume way more than needed. In other words, it is a perfect tool to help you gain weigth.
Of course, I'm not talking here about occasional can of Diet Coke here and there, but consumption of 2-3 cans per day or more.
There are numerous studies that clearly talk about this well-researched effect.
You can even look around yourself and see connection between overconsumption and Diet drinks. I've seen people eating 2000+ calories meal and feeling being on diet just by the fact that Diet Coke is next to them.....
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
Also diet coke is the drink of choice for many anorexics
So by MFP standards, it causes anorexia? Lol.
9 -
25+ years of drinking at least 2 cans a day. I'm cancer proof so far. If I get cancer, it'll probably lung cancer from being a previous smoker, not from drinking diet soda for so long.
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
3 -
singingflutelady wrote: »Overall, I agree with the original explanation of very little to no proof that aspartame causes cancer. There are far worse things around us that are making people sick.
That is not my worry about it. What I think this article is missing is a big point that aspartame affects insulin levels as much as sugar, and causes people to easily overeat and consume way more than needed. In other words, it is a perfect tool to help you gain weigth.
Of course, I'm not talking here about occasional can of Diet Coke here and there, but consumption of 2-3 cans per day or more.
There are numerous studies that clearly talk about this well-researched effect.
You can even look around yourself and see connection between overconsumption and Diet drinks. I've seen people eating 2000+ calories meal and feeling being on diet just by the fact that Diet Coke is next to them.....
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
Also diet coke is the drink of choice for many anorexics
So by MFP standards, it causes anorexia? Lol.
Apparently! Ed treatment centers ban diet drinks and if you want to drink pop you have to drink regular so yes it obviously causes anorexic3 -
Carlos_421 wrote: »ThatUserNameIsAllReadyTaken wrote: »Sorry but you don't get to decide what is "scary" to others.
But he does have the right to share valuable information regarding the reasons why there is nothing to fear.
You don't get to decide what is scary to others. Fear is an individual feeling. No matter what information you have. And that information's "value" is also an individual opinion. Why try to force something on people who don't want it. Just carry on enjoying your aspartame. There is no reason to force others to like it also.1 -
brentfostwood904 wrote: »brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Just to be clear, i would have to drink 3200mg of aspatame. Considering there is about 180mg in a can of diet coke, i would have to drink about 17 cans a day (this is at 40mg/kg of body weight as done by the study).
Soo...... i think i am good.
they chose the amount specifically because the FDA says that amount is safe. Yet the study proves that this amount in fact is not safe. The study was only for 90 days, if lower rates of aspartame simply cause a lower rate of damage then if youre looking at a lifetime of consuming it, you will still have more neuron death than the rats did in this study. If youre looking at 1 can of diet coke a day then you could say 90 days x 17 = 4 years for you to get to the same amount of neuron death as the rats in the study suffered in 90 days. Also, the neuron death was very significant, even a fraction of that would be bad. So I dont think anyone is good when they are eating aspartame. But that's just my advice to you.
Its also proof that it is a carcinogen, as it showed that free radicals were increased due to the aspartame.
I've had personal experience with someone who drank around 8 cans of diet coke a day for 10 years and yes her memory was very bad and the addiction was very real. I do not think it's just a coincidence that she happened to have memory problems when aspartame is proven to damage the hippocampus.
Argue that you think it's really safe if you want and keep on drinking it, I dont mind. But I wouldnt drink it. There are a lot more studies out there if you want to read up on it, I just chose that one at random really because it looked well done. It's your life anyway.
None of this has even shown to translate into humans. Also, context and dosage apply. Rats taking in their body weight in aspartame is bad. You cannot state the same for normal amounts of aspartame. It doesn't work like that. You would have to test rats at normal intake levels. Heck, even water has toxic levels. And just because it has toxic levels doesn't mean you can generalize it and say all levels of water are toxic. Do you know that apples contain cyanide?
It goes against the required reserach ethics to perform a damaging study on human subjects, which is why the closest available and ethically approved thing has to be used instead, in this case it is rats which were actually manipulated to make their metabolism more in line with human metabolism (something ignored in a lot of studies and something great about this one). They did not take their body weight in aspartame, they took 40mg per kg of bodyweight, which is the amount which the FDA says is safe for human consumption. The argument that "oh anything is poisonous in high enough quantities" does not apply here.2 -
Carlos_421 wrote: »brentfostwood904 wrote: »brentfostwood904 wrote: »aspartame overexcites neurons in the brain, causing them to die, in specific areas such as the hippocampus. Animal studies with aspartame have shown a hole in the hippocampus being caused by aspartame. My ex girlfriend who is now 21 used to drink about 8 cans of diet coke every day for years since the age of 12, and her memory is terrible, I fully believe the link to neuron death due to aspartame and I've seen how addictive it can get (she could not deal with not having diet coke at all and any aspartame free substitute did not work). It is something which is both addictive and causes death of neurons. Best avoided.
Do you have a source for this claim?
go and check out the animal model studies on aspartame and the hippocampus, theres a lot more than one out there. Read the long term studies because a lot of the short term studies say there is no effect.. but they are done over a stupid amount of time like 2 days.. so these ones are hardly well designed studies.
The studies that implicate aspartame causing problems in animals use such ridiculous quantities of aspartame that you'd have to drink thousands of gallons of diet soda per day in order to get a comparable amount in your diet.
Even if humans would suffer the same side effects that the mice did in these studies (which we don't even know that we would), if you drink enough diet soda to attain sufficient aspartame to see those side effects, you would die the first day due to over-hydration flushing your body of electrolytes.
no you are wrong, there are many out there which specifically use the amount that the FDA says is safe for human consumption. Actually any study which used a stupid amount should be ignored. But most of the ones I've read did not use a ridiculous amount.1 -
stevencloser wrote: »brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
For your reading pleasure:
http://seriecientifica.org/sites/default/files/scl_enc_butchko.pdf
http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2013.EN-399/pdf
The first one you linked is by "scientists" from "Research and Development, The NutraSweet Company," Meaning there is a very strong research bias. Meaning I know that the study is worthless before even continuing to read beyond the first few lines. If you want to find a decent study on anything then try to find one where there is no research bias or conflict of interest in the people involved. (These people get paid by NutraSweet to produce research which says that NutraSweet products are safe, this is something you must be aware of when reading any kind of research).
The second one I dont have time to read through right now but I might get back to you later.
1 -
brentfostwood904 wrote: »aspartame overexcites neurons in the brain, causing them to die, in specific areas such as the hippocampus. Animal studies with aspartame have shown a hole in the hippocampus being caused by aspartame. My ex girlfriend who is now 21 used to drink about 8 cans of diet coke every day for years since the age of 12, and her memory is terrible, I fully believe the link to neuron death due to aspartame and I've seen how addictive it can get (she could not deal with not having diet coke at all and any aspartame free substitute did not work). It is something which is both addictive and causes death of neurons. Best avoided.
You have two big holes in your brain, they are called ventricles. By what mechanism is this neurotoxicity inferred? I have a degree in neuroscience so I'm pretty confident I can evaluate the research.5 -
brentfostwood904 wrote: »stevencloser wrote: »brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
For your reading pleasure:
http://seriecientifica.org/sites/default/files/scl_enc_butchko.pdf
http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2013.EN-399/pdf
The first one you linked is by "scientists" from "Research and Development, The NutraSweet Company," Meaning there is a very strong research bias. Meaning I know that the study is worthless before even continuing to read beyond the first few lines. If you want to find a decent study on anything then try to find one where there is no research bias or conflict of interest in the people involved. (These people get paid by NutraSweet to produce research which says that NutraSweet products are safe, this is something you must be aware of when reading any kind of research).
The second one I dont have time to read through right now but I might get back to you later.
Discrediting science based on funds shows a lack of understand for how research is conducted. You need to understand the parameters of the study and evaluate the techniques... not the source of money. All studies must receive funding somehow. You really should watch the video I posted. Layne Norton is a very well respected scientist and has first hand knowledge. He even addresses your fund concerns.
And under the parameters of your study, it would never translate to humans.5 -
diannethegeek wrote: »This thread.
But not as cute.1 -
brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Oh God, not another rat brain study. You have to be VERY careful about those studies, although they can be useful markets there have been no studies that have actually shown these neurotoxic issues in humans who consume artificial sweetners unlike, for instance, studies of those who play contact sports or drink large amounts of alcohol yet we see a lot less panic in those. The primary suspicion is on methanol and it's metabolites, which are known already to be problematic but as mentioned by the OP, aspartame is a very small contributor to methanol in the body and increases in free radicals. Other foods, that nobody has an issue with, are higher as he already pointed out. Also, I notice they used mice that did not have folate production and where on a folate deficient diet (to "mimic" humans) and this itself could be an issue since they are likely aware that normal mice would not suffer from these effects. It might also not be very useful for humans who are not folate deficient.
So, yes, we can show potential damage in lab rats but translating that information into humans in the wild is not something that has been demonstrated. The number of lab rat studies that have shown "proof" of something yet failed to show these results in humans is legion so it's an indicator of a potential but not necessarily evidence of issues in humans.
ETA, also noticed that the dosage was really high. 40mg/kg bw is 2160 mg/day for a 120lb person and diet coke has 500mg per L (approx. 32oz). That would be a lot of diet coke to drink in a day.4 -
ThatUserNameIsAllReadyTaken wrote: »Carlos_421 wrote: »ThatUserNameIsAllReadyTaken wrote: »Sorry but you don't get to decide what is "scary" to others.
But he does have the right to share valuable information regarding the reasons why there is nothing to fear.
You don't get to decide what is scary to others. Fear is an individual feeling. No matter what information you have. And that information's "value" is also an individual opinion. Why try to force something on people who don't want it. Just carry on enjoying your aspartame. There is no reason to force others to like it also.
A.C.E. Certified Personal and Group Fitness Trainer
IDEA Fitness member
Kickboxing Certified Instructor
Been in fitness for 30 years and have studied kinesiology and nutrition
4 -
ThatUserNameIsAllReadyTaken wrote: »Carlos_421 wrote: »ThatUserNameIsAllReadyTaken wrote: »Sorry but you don't get to decide what is "scary" to others.
But he does have the right to share valuable information regarding the reasons why there is nothing to fear.
You don't get to decide what is scary to others. Fear is an individual feeling. No matter what information you have. And that information's "value" is also an individual opinion. Why try to force something on people who don't want it. Just carry on enjoying your aspartame. There is no reason to force others to like it also.
Fear is indeed an individual feeling which is why a parent doesn't get to decide whether or not their child will be afraid of the monster under their bed. However, the individuality of that child's fear doesn't negate the validity of the parent's reassurance that there is no such monster under the bed just like an individual's fear of aspartame doesn't negate the validity of the reassurances offered in this thread that it is perfectly safe as evidenced by decades of scientific research.
Your saying that if someone is afraid of aspartame we should say "oh, well then you better stay away from it then" even though we know that there is no reason to fear it.
Would you tell a child afraid of monsters "oh, well then you better not go in the closet" even though you know the scariest thing in there is a Christmas sweater?13 -
brentfostwood904 wrote: »brentfostwood904 wrote: »brentfostwood904 wrote: »here is a nice study for people if you cant find them so easily yourself http://www.sciencedirect.com/science/article/pii/S2213231714000640
Just to be clear, i would have to drink 3200mg of aspatame. Considering there is about 180mg in a can of diet coke, i would have to drink about 17 cans a day (this is at 40mg/kg of body weight as done by the study).
Soo...... i think i am good.
they chose the amount specifically because the FDA says that amount is safe. Yet the study proves that this amount in fact is not safe. The study was only for 90 days, if lower rates of aspartame simply cause a lower rate of damage then if youre looking at a lifetime of consuming it, you will still have more neuron death than the rats did in this study. If youre looking at 1 can of diet coke a day then you could say 90 days x 17 = 4 years for you to get to the same amount of neuron death as the rats in the study suffered in 90 days. Also, the neuron death was very significant, even a fraction of that would be bad. So I dont think anyone is good when they are eating aspartame. But that's just my advice to you.
Its also proof that it is a carcinogen, as it showed that free radicals were increased due to the aspartame.
I've had personal experience with someone who drank around 8 cans of diet coke a day for 10 years and yes her memory was very bad and the addiction was very real. I do not think it's just a coincidence that she happened to have memory problems when aspartame is proven to damage the hippocampus.
Argue that you think it's really safe if you want and keep on drinking it, I dont mind. But I wouldnt drink it. There are a lot more studies out there if you want to read up on it, I just chose that one at random really because it looked well done. It's your life anyway.
None of this has even shown to translate into humans. Also, context and dosage apply. Rats taking in their body weight in aspartame is bad. You cannot state the same for normal amounts of aspartame. It doesn't work like that. You would have to test rats at normal intake levels. Heck, even water has toxic levels. And just because it has toxic levels doesn't mean you can generalize it and say all levels of water are toxic. Do you know that apples contain cyanide?
It goes against the required reserach ethics to perform a damaging study on human subjects, which is why the closest available and ethically approved thing has to be used instead, in this case it is rats which were actually manipulated to make their metabolism more in line with human metabolism (something ignored in a lot of studies and something great about this one). They did not take their body weight in aspartame, they took 40mg per kg of bodyweight, which is the amount which the FDA says is safe for human consumption. The argument that "oh anything is poisonous in high enough quantities" does not apply here.
I fail to see how submitting humans to a study in which they are prescribed a substance in quantities deemed safe by the FDA would violate any ethical standards.3
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