Is It Over Yet? The Perimenopause Thread
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ThatUserNameIsAllReadyTaken wrote: »Just came across this. I have been doing a lot of digging on this perimenopause thing. There are so many crazy things that women experience.
nature.com/nrendo/journal/v11/n7/abs/nrendo.2015.82.html
Unless I'm missing something, it appears you have to pay for access to this article?0 -
ThatUserNameIsAllReadyTaken wrote: »Just came across this. I have been doing a lot of digging on this perimenopause thing. There are so many crazy things that women experience.
nature.com/nrendo/journal/v11/n7/abs/nrendo.2015.82.html
Unless I'm missing something, it appears you have to pay for access to this article?
I did not have to pay. That's strange! Is it a popup asking you to pay?0 -
I just clicked on it to make sure and it did not ask me to pay to view the article.0
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ThatUserNameIsAllReadyTaken wrote: »ThatUserNameIsAllReadyTaken wrote: »Just came across this. I have been doing a lot of digging on this perimenopause thing. There are so many crazy things that women experience.
nature.com/nrendo/journal/v11/n7/abs/nrendo.2015.82.html
Unless I'm missing something, it appears you have to pay for access to this article?
I did not have to pay. That's strange! Is it a popup asking you to pay?
I can only read the intro, and it doesn't allow me to click on "read more". Down below it says you have to subscribe or purchase a copy to read the rest.1 -
ThatUserNameIsAllReadyTaken wrote: »I just clicked on it to make sure and it did not ask me to pay to view the article.
Do you subscribe to the website?0 -
Just tried it again. When I click on "view full text", the intro just comes up again and the box below says you need to be a subscriber to finish it.0
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ThatUserNameIsAllReadyTaken wrote: »I just clicked on it to make sure and it did not ask me to pay to view the article.
Do you subscribe to the website?
I do not subscribe. I will copy and paste the article here though. I will make a note of that website and what it is doing, maybe I won't post any links from there anymore if that is what happens.
"Perimenopause is a midlife transition state experienced by women that occurs in the context of a fully functioning neurological system and results in reproductive senescence. Although primarily viewed as a reproductive transition, the symptoms of perimenopause are largely neurological in nature. Neurological symptoms that emerge during perimenopause are indicative of disruption in multiple estrogen-regulated systems (including thermoregulation, sleep, circadian rhythms and sensory processing) and affect multiple domains of cognitive function. Estrogen is a master regulator that functions through a network of estrogen receptors to ensure that the brain effectively responds at rapid, intermediate and long timescales to regulate energy metabolism in the brain via coordinated signalling and transcriptional pathways. The estrogen receptor network becomes uncoupled from the bioenergetic system during the perimenopausal transition and, as a corollary, a hypometabolic state associated with neurological dysfunction can develop. For some women, this hypometabolic state might increase the risk of developing neurodegenerative diseases later in life. The perimenopausal transition might also represent a window of opportunity to prevent age-related neurological diseases. This Review considers the importance of neurological symptoms in perimenopause in the context of their relationship to the network of estrogen receptors that control metabolism in the brain."
There ya go. That is all it has for me to red, not sure if that was what you were able to see or not.2 -
Now MFP is telling me my comments need to be "approved" before I can post? Seriously?0
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ThatUserNameIsAllReadyTaken wrote: »ThatUserNameIsAllReadyTaken wrote: »I just clicked on it to make sure and it did not ask me to pay to view the article.
Do you subscribe to the website?
I do not subscribe. I will copy and paste the article here though. I will make a note of that website and what it is doing, maybe I won't post any links from there anymore if that is what happens.
"Perimenopause is a midlife transition state experienced by women that occurs in the context of a fully functioning neurological system and results in reproductive senescence. Although primarily viewed as a reproductive transition, the symptoms of perimenopause are largely neurological in nature. Neurological symptoms that emerge during perimenopause are indicative of disruption in multiple estrogen-regulated systems (including thermoregulation, sleep, circadian rhythms and sensory processing) and affect multiple domains of cognitive function. Estrogen is a master regulator that functions through a network of estrogen receptors to ensure that the brain effectively responds at rapid, intermediate and long timescales to regulate energy metabolism in the brain via coordinated signalling and transcriptional pathways. The estrogen receptor network becomes uncoupled from the bioenergetic system during the perimenopausal transition and, as a corollary, a hypometabolic state associated with neurological dysfunction can develop. For some women, this hypometabolic state might increase the risk of developing neurodegenerative diseases later in life. The perimenopausal transition might also represent a window of opportunity to prevent age-related neurological diseases. This Review considers the importance of neurological symptoms in perimenopause in the context of their relationship to the network of estrogen receptors that control metabolism in the brain."
There ya go. That is all it has for me to red, not sure if that was what you were able to see or not.
That's the abstract. There's a research article after it, that costs money.0 -
ThatUserNameIsAllReadyTaken wrote: »ThatUserNameIsAllReadyTaken wrote: »I just clicked on it to make sure and it did not ask me to pay to view the article.
Do you subscribe to the website?
I do not subscribe. I will copy and paste the article here though. I will make a note of that website and what it is doing, maybe I won't post any links from there anymore if that is what happens.
"Perimenopause is a midlife transition state experienced by women that occurs in the context of a fully functioning neurological system and results in reproductive senescence. Although primarily viewed as a reproductive transition, the symptoms of perimenopause are largely neurological in nature. Neurological symptoms that emerge during perimenopause are indicative of disruption in multiple estrogen-regulated systems (including thermoregulation, sleep, circadian rhythms and sensory processing) and affect multiple domains of cognitive function. Estrogen is a master regulator that functions through a network of estrogen receptors to ensure that the brain effectively responds at rapid, intermediate and long timescales to regulate energy metabolism in the brain via coordinated signalling and transcriptional pathways. The estrogen receptor network becomes uncoupled from the bioenergetic system during the perimenopausal transition and, as a corollary, a hypometabolic state associated with neurological dysfunction can develop. For some women, this hypometabolic state might increase the risk of developing neurodegenerative diseases later in life. The perimenopausal transition might also represent a window of opportunity to prevent age-related neurological diseases. This Review considers the importance of neurological symptoms in perimenopause in the context of their relationship to the network of estrogen receptors that control metabolism in the brain."
There ya go. That is all it has for me to red, not sure if that was what you were able to see or not.
Yep- that's just the intro. Which was interesting & made me want to read more
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For those considering hormones, birth control pills contain a higher dose of hormones than traditional HRT. I stopped being able to tolerate hormonal birth control in my 30s. However, I have had no issues tolerating HRT and the improvement in energy levels and general quality of life has been significant. I have been on it for about two years at this point. The newer theories say it's better to go on it fairly early in the meno timeline. I'm on an estrogen patch (most are bio-identical) and synthetic progesterone. The only reason to go on BC pills over HRT is if you want to regulate your cycle. I have a very light period about every four months at this point, and that's acceptable to me.0
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This bears reposting:
http://www.34-menopause-symptoms.com
I strongly encourage women in peri- to read a couple of books, or at least spend time on a couple of good websites (like the north american menopause society).
Symptoms like: vertigo, low blood sugar, itchy skin.... all we ever really hear about is the eventual hot flashes.
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Someone apparently flagged me for spam. I was making NO attempt at spam. Trying to share something I found interesting has turned into an absurd fiasco. I can't post with out approval now. So whatever. Anyone who is interested in the neurological aspect of perimenopause will hopefully find something else on it.0
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Sabine_Stroehm wrote: »Symptoms like: vertigo, low blood sugar, itchy skin.... all we ever really hear about is the eventual hot flashes.
Yes- I actually thought that since I haven't had hot flashes (yet) and my periods are still somewhat regular, that maybe that wasn't the issue. Never mind the dozens of other symptoms that I've had!
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ThatUserNameIsAllReadyTaken wrote: »Someone apparently flagged me for spam. I was making NO attempt at spam. Trying to share something I found interesting has turned into an absurd fiasco. I can't post with out approval now. So whatever. Anyone who is interested in the neurological aspect of perimenopause will hopefully find something else on it.
Maybe if you post a link to such a site, it automatically triggers something in the MFP system? No biggie to me- I didn't think you were promoting anything.1 -
ThatUserNameIsAllReadyTaken wrote: »Now MFP is telling me my comments need to be "approved" before I can post? Seriously?
I had that a little while ago when I included a link to an article in one of my posts - might be some automatic spam-reduction thingy within MFP, as mentioned? *shrug* I didn't think you were being spammy either!
Been reading this thread for a while now but not commented on it yet, but there's some useful and interesting posts and links here! I never realised that some of the things I've been experiencing over the past few months might be related to perimenopause. (Memory and concentration issues I figured were just due to age and lack of actually using my brain lately! And I never would have thought dizziness and tingling fingers might have a hormonal cause.)
Thanks to everyone who's sharing their experiences here, it's very helpful!2 -
ThatUserNameIsAllReadyTaken wrote: »Been reading this thread for a while now but not commented on it yet, but there's some useful and interesting posts and links here! I never realised that some of the things I've been experiencing over the past few months might be related to perimenopause. (Memory and concentration issues I figured were just due to age and lack of actually using my brain lately! And I never would have thought dizziness and tingling fingers might have a hormonal cause.)
Yes, Sue! I was actually becoming concerned about dementia because of the sudden, dramatic memory loss and how often I would find myself thinking in circles! That's why I was interested in the link above- I had no idea estrogen was so instrumental to our brain function.0 -
ThatUserNameIsAllReadyTaken wrote: »Been reading this thread for a while now but not commented on it yet, but there's some useful and interesting posts and links here! I never realised that some of the things I've been experiencing over the past few months might be related to perimenopause. (Memory and concentration issues I figured were just due to age and lack of actually using my brain lately! And I never would have thought dizziness and tingling fingers might have a hormonal cause.)
Yes, Sue! I was actually becoming concerned about dementia because of the sudden, dramatic memory loss and how often I would find myself thinking in circles! That's why I was interested in the link above- I had no idea estrogen was so instrumental to our brain function.
Obviously my brain wasn't working when I performed that quote!0 -
Now I just don't know what's going on! ???0
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"See ya next year..." Revenge of the Brigadoon Period.
Ok, this totally made me laugh. I'm picturing Gene Kelly giving Cyd Charisse a pack of tampons.ETA: Oh! Anybody get serious PMS-ish feeling but no period, periodically? (
) And the associated symptoms you used to get, including bloating/gain?
I do, but I unrelated to menopause, I think. I have PCOS, so periods are random and few. When I work out and my hormonal situation improves, I get regular PMS symptoms but still no actual M. It's unclear on what menopause will look like. My mother had her last period at 56, so it seems like I've got about 10 more years of weirdness.1 -
Oh, yeah, the PMS symptoms... I still get mood swings, breast tenderness, hunger pangs and sometimes even cramps, but I don't often get a period now. It's like everything else happens BUT the actual period! Or sometimes it'll be just very light for a couple of days. And sometimes I get a surprise visit from Auntie with no warning whatsoever. It sucks just never knowing if something is going to happen or not! Last year I went for a few months with nothing at all, then had three in the space of about 8 weeks. Bah! Why can't it just be over and done with?!
I was feeling quite grateful that I've rarely had the "usual" symptoms like hot flashes (I had a few a couple of years ago but not for some time now), but having read that list I realise I probably have a bunch of others that I'd never associated with the process.
And yeah, I was getting concerned about dementia too, since my mum had Alzheimer's. My memory's never been quite as good as it used to be ever since I was pregnant (I heard that memory issues are common during pregnancy but it's supposed to improve after the birth!), but I've definitely been getting worse over the last few months. I think poor concentration and stuff can also be one of the symptoms of depression as well, though, so I'm not sure exactly what's causing it. Maybe I need to dig out a quantum physics book and really make my brain work hard!!
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Is it over yet? Will it ever be over? Who knows...in the meantime...shout out if you're peri!
According to my newest gynaecologist, who I saw for the first time today, the whole perimenopause process takes approx. 10 years.
Based on what I told him about the last few years of my life, his best guess is that I was definitely into perimenopause in 2012. And based on the symptoms I was showing in 2012, I likely started perimenopause in about 2010.
10 years puts me at 2020 before the whole thing is complete ... in other words, I've gone a full 12 months with no period.
So he figures I've got about another 2 years of wonky strange frustrating periods left.
Incidentally, the reason I had to go see my newest gynaecologist is because he is also an oncologist. He specialises in female cancers.
On Dec 6, I was diagnosed with pre-cancer.
A couple years ago, I was diagnosed with, essentially, pre-pre-cancer of the uterus and so I have to go for testing every 6 months to monitor that. So far so good. This newest thing is in an adjacent area and fortunately is a low-grade, slow developing version.
Therefore my gynaecological oncologist has opted for the monitoring route. I may have to go for biopsies every 6 months or so. My next appointment has already been scheduled for May.
Happily, he actually said to me that because I am "fit, strong, and slender" (his words!) I should be able to fight it. And that on a day when I was feeling particularly bloated and large.
Fortunately he is also familiar with my genetic disorder. I've mentioned it to other gynaecologists who have had some vague familiarity with it but haven't been sure what's involved. This one knew all about it, and told me that under no circumstances am I to have anything to do with hormone therapy. Absolutely not! Others have been saying things like, it's low dose and might be OK ... this one said, "No.".
Anyway, he figures much of the weirdness going on is perimenopause, but some of it could be related to this pre-cancer business.
Moral of the story ... get checked!
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TheGaudyMagpie wrote: »For those considering hormones, birth control pills contain a higher dose of hormones than traditional HRT. I stopped being able to tolerate hormonal birth control in my 30s. However, I have had no issues tolerating HRT and the improvement in energy levels and general quality of life has been significant. I have been on it for about two years at this point. The newer theories say it's better to go on it fairly early in the meno timeline. I'm on an estrogen patch (most are bio-identical) and synthetic progesterone. The only reason to go on BC pills over HRT is if you want to regulate your cycle. I have a very light period about every four months at this point, and that's acceptable to me.
Definitely. Most HRT is much lower. And yes, there are more options.
The Estrogen Window (book) reviews the flaws with the famous study that cast such a shadow on HRT, and discusses the benefits and risks of HRT at various ages.
My library had it on HOOPLA (digital library rental iphone/android app). Worth checking out.
I also wasn't able to tolerate hormonal BC after my 20s.
I use bio-identical progesterone now, and and pondering bio-identical estrogen now that my period has (in theory) totally stopped. If I do, it will be bio-identical for sure.1 -
Here's something I've been wondering for awhile. Maybe some of you will know the answer from your experiences. I am 46 years old. I've been on bc pills since I was 18. For the past two years, I've been taking them continuously which means I don't have a period (although I have lots of spotting). How will I know when I'm in menopause if I'm on the pill? Any insight?1
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You may not know. Eventually, you'll have to stop taking the pill. Then, if you're menopausal, you'll have symptoms (unless you go straight to HRT, which I wouldn't recommend). If you're peri-menopausal you may have symptoms and a period. But otherwise, you may not know. OR, as with a friend, symptoms popped up on top of the BC pill.Here's something I've been wondering for awhile. Maybe some of you will know the answer from your experiences. I am 46 years old. I've been on bc pills since I was 18. For the past two years, I've been taking them continuously which means I don't have a period (although I have lots of spotting). How will I know when I'm in menopause if I'm on the pill? Any insight?
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ThatUserNameIsAllReadyTaken wrote: »Someone apparently flagged me for spam. I was making NO attempt at spam. Trying to share something I found interesting has turned into an absurd fiasco. I can't post with out approval now. So whatever. Anyone who is interested in the neurological aspect of perimenopause will hopefully find something else on it.
@ThatUserNameIsAllReadyTaken my account once got the spam block from the automatic system (rather than from a moderator) and I wrote to @Alex, who fixed it.0 -
I think it's done now. I haven't seen the pop up telling me my comment had to be approved anymore. However the comments that never were approved are still a mystery to me. I can't imagine what I said that was so "spammy" that they chose not to post my comments. I'm just moving on at this point.1
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