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Please help with this argument- Intermittent fasting related

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  • Posts: 8,940 Member
    edited September 2019
    mmapags wrote: »

    Yeah, it's amazing how frequently people jump on some clickbait about IF. The majority of them are mouse studies which may or may not translate to humans. A small % of mouse studies typically do.

    There have been mostly short term, low participant and often uncontrolled studies on IF with human participants. More in depth, high quality human studies would certainly be beneficial. As of now, none of these auxiliary benefits are proven. As a person who practices IF, I hope there are more benefits. But I'm not going to claim them and act on them until there is proof. We should all recall how fat was the boogie man in the 70s and 80s based on insufficient evidence...

    If someone else want to be an early adapter and bet on the come, that is up to them but don't claim it as fact please and using mouse studies only undermines your credibility.

    I am with you. I hope IF is proven to have all kinds of benefits. I have never said that none exist. But I have heard of miracle cures and fat burning secrets my entire life and none of them have ever stood against the test of science.

    My personal theory has always been that some of the benefits may exist in humans but they they are so tiny they are hard to measure. If a person like me that has skipped breakfast for 20+ years had been measured back in the beginning and now perhaps something will have shown up.

    While I would never try to connect this when I do read about this improvement in insulin resistance I sometimes find myself wondering if my 20+ years of "improving" might have contributed to my reactive hypoglycemia. My body produces too much insulin. On the other hand that would be a great clickbait blog: Can long term IF cause your blood sugar to drop to fatal levels? Find out here!
  • Posts: 28,055 Member
    raven56706 wrote: »
    haha i think this debate was more entertaining here than the one with my friend.

    MFP brings the lulz!
  • Posts: 10,213 Member
    NovusDies wrote: »

    I am with you. I hope IF is proven to have all kinds of benefits. I have never said that none exist. But I have heard of miracle cures and fat burning secrets my entire life and none of them have ever stood against the test of science.

    My personal theory has always been that some of the benefits may exist in humans but they they are so tiny they are hard to measure. If a person like me that has skipped breakfast for 20+ years had been measured back in the beginning and now perhaps something will have shown up.

    While I would never try to connect this when I do read about this improvement in insulin resistance I sometimes find myself wondering if my 20+ years of "improving" might have contributed to my reactive hypoglycemia. My body produces too much insulin. On the other hand that would be a great clickbait blog: Can long term IF cause your blood sugar to drop to fatal levels? Find out here!


    This reminds me of my own longtime personal theory that the outsized benefits attributed to relatively small weight losses in the significantly overweight or obese (say, 5% to 10% of BW) confound the benefits of weight loss with the benefits of being in a calorie deficit -- that is, that there could be effects on some of the common health markers such as blood glucose, BP, lipid profiles caused by being in a calorie deficit over a period of weeks (presumably it would be an effect of the physical processes needed to recover stored energy), totally separate from the benefits of being a slightly healthier weight. I'm wondering if simply being in a calorie deficit for longer periods each day, which could cause more recovery of stored energy during that period (even if counterbalanced by energy storage in the eating window), could have similar effects.
  • Posts: 1,120 Member
    For tens of thousands of years or forbears were hunter gatherers. They didn't do so when they realized that they were hungry, or at a certain time (no watches, only the sun, moon and stars to guide them) or only after a certain amount of hours - how would they have known? And they hunted and gathered all the time. I prefer to eat something at home before I start my "hunting gathering" at the shopping centre / supermarket, i.e. do my food and beverage shopping. And I never enjoyed a big breakfast - an early lunch seems to suit me just fine which means that between dinner time (about 7 p.m.) and the next meal are about 16 to 18 hours. Call that intermittent fasting? Fine by me - I just wonder who told my stomach to behave like that...
  • Posts: 8,940 Member


    This reminds me of my own longtime personal theory that the outsized benefits attributed to relatively small weight losses in the significantly overweight or obese (say, 5% to 10% of BW) confound the benefits of weight loss with the benefits of being in a calorie deficit -- that is, that there could be effects on some of the common health markers such as blood glucose, BP, lipid profiles caused by being in a calorie deficit over a period of weeks (presumably it would be an effect of the physical processes needed to recover stored energy), totally separate from the benefits of being a slightly healthier weight. I'm wondering if simply being in a calorie deficit for longer periods each day, which could cause more recovery of stored energy during that period (even if counterbalanced by energy storage in the eating window), could have similar effects.

    I don't know. I do know that my lipids have gone the wrong way which seems to also be a thing with people who have a lot of fat to lose and are not weight stable.

    I am not sure if my BP will actually improve until I have my surgery and can incorporate more exercise. It hasn't changed in nearly 150 pounds but it is only mildly high. Before medication 125-135/69-78 was my normal range. I apparently never needed any help with my RHR which has remained around 55 for the last 100 pounds or so I have bothered to add it to my SS.

    I do find the various changes in physiology to be very interesting while in a deficit. I had no idea it could change hormone levels so much.
  • Posts: 18,842 Member
    @heybales, have you ever considered ordering your own blood work and paying for it? That’s what I do. I’m self-employed and have a high-deductible health insurance plan and find it cheaper and easier to go this route. Besides, I never clear my deductible.

    I order various tests of interest to me every birthday. Last time included A1C for the first time because I was curious having read about it.

    This approach isn’t for everyone but it’s my approach. Been doing this for years. Not going to let some doc tell me what lab work I can and can’t have. I’m the boss with my health and willing to pay for it. It’s not that expensive.

    I will prior to next annual visit.
    Not only to get what I want on it - but also to go in with the results if there needs to be discussion. Rather than go in, get reference to downstairs lab to get it, then another appointment to come in to discuss it.
    And I'm sure the pre-insurance price on the EOB for the test isn't true for outside firm direct non-insurance payment.
  • Posts: 6,252 Member
    Intermittent fasting can be effective for those manging caloric intake. From the objective evidence most are susceptible to snacking during "downtime" when they are not as engaged, so implementing a deliberate fast during these times can be very effective.

    Outside of that there aren't many benefits that are demonstrable.
  • Posts: 2,111 Member

    I'm actually more excited about not-so-new things that are supported by multiple studies carried out by multiple researchers looking at a question from a variety of angles. There's a tendency for people to get all excited about some new study that shows something new, that might just be an outlier in the entire corpus of studies looking at an issue.

    All of those not so new things you are excited about were new once with minimal promising research which prompted more research.

    In the end we should all do what works for us but dismissing promising new research for the sole purpose that more still needs to be done is silly. No one will argue more research should still be conducted but that doesn’t discount the potential found in the research that has already been completed either.
  • Posts: 918 Member
    true but people have sworn by it. IF has helped many including Hugh Jackman and other celebs shed the weight for promotion.

    I just think that they were never able to get into a calorie intake for a deficit. For me, IF is just a tool to keep you from eating and maintain you in a deficit. No magic.
  • Posts: 78 Member
    @heybales, I use Direct Labs. Type www. then their name with no space and then .com and you’ll be on their home page. They have monthly specials so when I see what I’m interested in, I’ll stock up. I use my HSA card to pay.

    They send you a requisition form that you take to your local lab. I use Quest. You go in just like any other lab visit and then in about 48 hours, you get an email that your results are in. You then log in to your account and download the results. Absolutely seamless.

    If you decide to use, I’m sure you’ll be pleased. Wishing you the best.

    A bit ot, but thanks for the info! Since switching to a mostly carnivore style way of eating I want to get blood work more frequently than my doctor's annual panel, with some specific ones that wouldn't normally be included for a regular check-up (like the A1C, LDL-P test etc). I've been looking at some online options, but there's a lot of them out there so it's nice to have a recommendation :)
  • Posts: 2,468 Member
    There are some ways of practicing IF that I would find it hard to imagine someone eating enough within their eating window to gain weight. An example would be someone who only eats during a four hour window every 24 hours. Sticking to that, I myself can't imagine being able to eat enough in four hours to gain weight, even if I think of caloric high density foods. Honestly eating enough to maintain in six hours seems difficult, if not very uncomfortable.
  • Posts: 10,213 Member
    SCoil123 wrote: »

    All of those not so new things you are excited about were new once with minimal promising research which prompted more research.

    In the end we should all do what works for us but dismissing promising new research for the sole purpose that more still needs to be done is silly. No one will argue more research should still be conducted but that doesn’t discount the potential found in the research that has already been completed either.

    And there have been far, far more new things that people get excited about that turn out not to be replicable in later studies. Seems like a lot of excitement wasted at a stage when it's pretty much impossible to know which camp a particular study falls into.
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