Coronavirus prep

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  • jenilla1
    jenilla1 Posts: 11,118 Member
    JustSomeEm wrote: »
    USA Today has a story reporting the timeline and results of the virus from 1918. It’s interesting how similar our situation is today. I can’t copy the link, but the reporter’s name is Grace Hauck, and the article was 11/22/20. Check it out.

    Thanks for that - interesting read. Here's the link for anyone interested: https://www.usatoday.com/in-depth/news/nation/2020/11/21/covid-and-thanksgiving-how-we-celebrated-during-1918-flu-pandemic/6264231002/

    While looking for that one, I also found this one which is also interesting and sad: https://www.whio.com/news/trending/1918-flu-pandemic-letters-shed-light-how-similar-coronavirus-pandemic-is-past-outbreak/S4MMHFYC6RAP7AJ7KNK5TWAOVQ/

    Wow. It really IS similar. It's almost like history repeating itself...thanks for the links.
  • snowflake954
    snowflake954 Posts: 8,399 Member
    Italy--A famous historian was asked about past pandemics and he noted how similar they were with COVID. EVEN with modern medicine the course is similar. Modern man thinks he can beat this with science, whereas there was resignation and prayers in the past. It's frightening how this monster just keeps advancing.
  • kimny72
    kimny72 Posts: 16,010 Member
    kimny72 wrote: »
    The folks at This Week in Virology are REALLY excited about mRNA vaccines. They looked at whatever public data was available for the Pfizer and Moderna vaccines, and said that while it's still on a small scale, the numbers are far better than they expected. And there is a hint that even if someone who is vaccinated becomes infected, they will be more likely to have a mild case. And if both companies are able to produce the vaccine at the levels they are advertising, that will be impressive as well.

    They said that if these numbers turn out to be even close to accurate on a large scale, the "discovery" of mRNA vaccination will be one of the most impressive successes in modern medicine. There is already work being done to see if this technology can be used on other viruses that no effective vaccine has been possible for previously, or improved efficacy over existing vaccines. Basically, the mRNA particles were not discovered while trying to develop a vaccine - they were just being studied in labs as a curious new particle until someone noticed what they did and how they could be used and made the connection. Exciting stuff :smiley:

    Very interesting! I worked in a lab who was studying efficacy of mRNA influenza vaccines a few years ago. First we tested it on HEK293 cells and then proceeded to animals. One of the projects I worked on was testing the mRNA virus efficacy in preventing certain strains of flu in mice. We had great results and the group published quite a few papers on it. Their next big project was trying to get a grant to begin testing on human subjects. Haven't talked with them since I was a part of their lab a few years ago, but this reminded me I should email and see if they ever got the grant and what happened to the project.

    It is a lot better because it allows you to change the vaccine more quickly than using DNA and thus better match the vaccine for certain mutations and strain variants faster. I wonder if future COVID vaccines will use this technology. I think it depends on how fast the virus mutates and how many different strains are actually going around. (Which I don't think they quite know yet.)

    I'd bet projects like that will have a much better chance of getting grants as these first covid vaccines progress! They did mention something about flu vaccines, but I was lost in the scientific terminology weeds at that point :lol:
  • lkpducky
    lkpducky Posts: 18,607 Member
    kimny72 wrote: »
    They said that if these numbers turn out to be even close to accurate on a large scale, the "discovery" of mRNA vaccination will be one of the most impressive successes in modern medicine. There is already work being done to see if this technology can be used on other viruses that no effective vaccine has been possible for previously, or improved efficacy over existing vaccines. Basically, the mRNA particles were not discovered while trying to develop a vaccine - they were just being studied in labs as a curious new particle until someone noticed what they did and how they could be used and made the connection. Exciting stuff :smiley:

    Or even cancer
    Here's a good story of the history of mRNA therapeutics
    https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-once-dismissed-idea-became-a-leading-technology-in-the-covid-vaccine-race/?utm_source=pocket-newtab&fbclid=IwAR0s8kjoK4AhcuewJe7QkbzfolGcxfsLtQUme12VTcoViyhw08au6ufiRtU

  • lokihen
    lokihen Posts: 382 Member
    For my fellow Fresca lovers, I picked up a Walmart curbside order today and was able to get Fresca in two liter bottles.
  • SModa61
    SModa61 Posts: 3,465 Member
    There’s too much divisiveness. It’s nice to see posts clarifying and explaining. I’m thankful for the internet. Can you imagine how much more stressful 2020 would have been without being able to connect with others this easily?

    There was a song Jewel sang years ago. I often think about her words. “In the end, only kindness matters”.

    Hoping for a safe, happy, and love filled Thanksgiving for all❤️ Here’s hoping for a better 2021🍷

    All true
  • SModa61
    SModa61 Posts: 3,465 Member
    on another note,

    https://nypost.com/2020/11/23/cuomo-floats-hosting-his-mom-for-thanksgiving-setting-off-an-uproar/

    more recent articles imply he is now retracting his plans for his mother