Coronavirus prep
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https://thehill.com/policy/healthcare/other/539323-genetic-mutation-inherited-from-neanderthals-could-help-protect
Sounds like long term immunity perhaps?1 -
I couldn't find any information on this question but I'm curious, maybe someone here knows. Concerning receiving the Moderna vaccine, are recipients under age 55 known to have a tougher time with side effects than other age categories?
I read that younger people has more side effects after the second dose of Moderna, too. The theory is that they have a more robust immune system providing a stronger reaction after such second dose. The theory also speculates that, since older people immune system has been reduced by age, the response to the second jab may not be that bad.
I can't remember where I read that but if I find the article I will post it.
@RennieHJ
I just read that you had a mild case of COVID in November. Hopefully you were vaccinated 3 months after that. I read, and had friends to prove it, that vaccination side effects specially the second one, is tougher for people that had been previous infected. The reason is a double kick in the immune system.
It is OK to take Tylenol for fevers and body aches. Doctors recommend to stay away from Advil or other NSAIDs, since they "may" interfere with the action of the vaccines.
Woke up with the typical sore arm this a.m. We'll see what the day brings. I'm really tired today but it's because I was awake a lot last night; that happens to me some nights.
I was diagnosed with Covid a week before Thanksgiving so it might be just about 3 months, not sure.
Stay well everyone!!12 -
I couldn't find any information on this question but I'm curious, maybe someone here knows. Concerning receiving the Moderna vaccine, are recipients under age 55 known to have a tougher time with side effects than other age categories?
I read that younger people has more side effects after the second dose of Moderna, too. The theory is that they have a more robust immune system providing a stronger reaction after such second dose. The theory also speculates that, since older people immune system has been reduced by age, the response to the second jab may not be that bad.
I can't remember where I read that but if I find the article I will post it.
@RennieHJ
I just read that you had a mild case of COVID in November. Hopefully you were vaccinated 3 months after that. I read, and had friends to prove it, that vaccination side effects specially the second one, is tougher for people that had been previous infected. The reason is a double kick in the immune system.
It is OK to take Tylenol for fevers and body aches. Doctors recommend to stay away from Advil or other NSAIDs, since they "may" interfere with the action of the vaccines.
Woke up with the typical sore arm this a.m. We'll see what the day brings. I'm really tired today but it's because I was awake a lot last night; that happens to me some nights.
I was diagnosed with Covid a week before Thanksgiving so it might be just about 3 months, not sure.
Stay well everyone!!
Really glad your symptoms are mild. You should be fine then. 99% of the time the severe symptoms start in the first 24 hours.6 -
My 83 yo mom got her first shot Tuesday and that night felt like she was coming down with something. It's now Friday and she feels much better.15
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paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.9 -
paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.5 -
paperpudding wrote: »paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.
You have mentioned the interstate travel restrictions. How did this work in Australia? Was it the "honor system", just essentially asking people not to cross state borders, or were there actual checkpoints set up?
I ask because it simply wouldn't be feasible in the U.S. to close state borders. There are no real border crossings, just tourism signs that say "Welcome to Iowa" or wherever. As an example, my state, Illinois, borders 5 other states. For just one of those borders, there are 83 roads that cross from Illinois into Wisconsin (I looked at a map and counted). Most people cross that border using two interstate highways, but there's no way you could stop traffic on a 8-lane interstate to check IDs. It's just not possible.
With 48 states that share borders with other states, it's not even a serious topic of discussion from a logistical sense.8 -
SuzySunshine99 wrote: »paperpudding wrote: »paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.
You have mentioned the interstate travel restrictions. How did this work in Australia? Was it the "honor system", just essentially asking people not to cross state borders, or were there actual checkpoints set up?
I ask because it simply wouldn't be feasible in the U.S. to close state borders. There are no real border crossings, just tourism signs that say "Welcome to Iowa" or wherever. As an example, my state, Illinois, borders 5 other states. For just one of those borders, there are 83 roads that cross from Illinois into Wisconsin (I looked at a map and counted). Most people cross that border using two interstate highways, but there's no way you could stop traffic on a 8-lane interstate to check IDs. It's just not possible.
With 48 states that share borders with other states, it's not even a serious topic of discussion from a logistical sense.
I've driven in 48 states and crossed a lot of borders. The one state that is setup for this is California. They stop all traffic coming in and have done so for years. This includes 4 lane divided interstates.4 -
T1DCarnivoreRunner wrote: »SuzySunshine99 wrote: »paperpudding wrote: »paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.
You have mentioned the interstate travel restrictions. How did this work in Australia? Was it the "honor system", just essentially asking people not to cross state borders, or were there actual checkpoints set up?
I ask because it simply wouldn't be feasible in the U.S. to close state borders. There are no real border crossings, just tourism signs that say "Welcome to Iowa" or wherever. As an example, my state, Illinois, borders 5 other states. For just one of those borders, there are 83 roads that cross from Illinois into Wisconsin (I looked at a map and counted). Most people cross that border using two interstate highways, but there's no way you could stop traffic on a 8-lane interstate to check IDs. It's just not possible.
With 48 states that share borders with other states, it's not even a serious topic of discussion from a logistical sense.
I've driven in 48 states and crossed a lot of borders. The one state that is setup for this is California. They stop all traffic coming in and have done so for years. This includes 4 lane divided interstates.
California has 16 agricultural checkpoints at certain borders. The infrastructure and staffing are already there, including ways to efficiently move traffic through. It's not feasible for other states to try to create and staff checkpoints like that on the fly.4 -
SuzySunshine99 wrote: »T1DCarnivoreRunner wrote: »SuzySunshine99 wrote: »paperpudding wrote: »paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.
You have mentioned the interstate travel restrictions. How did this work in Australia? Was it the "honor system", just essentially asking people not to cross state borders, or were there actual checkpoints set up?
I ask because it simply wouldn't be feasible in the U.S. to close state borders. There are no real border crossings, just tourism signs that say "Welcome to Iowa" or wherever. As an example, my state, Illinois, borders 5 other states. For just one of those borders, there are 83 roads that cross from Illinois into Wisconsin (I looked at a map and counted). Most people cross that border using two interstate highways, but there's no way you could stop traffic on a 8-lane interstate to check IDs. It's just not possible.
With 48 states that share borders with other states, it's not even a serious topic of discussion from a logistical sense.
I've driven in 48 states and crossed a lot of borders. The one state that is setup for this is California. They stop all traffic coming in and have done so for years. This includes 4 lane divided interstates.
California has 16 agricultural checkpoints at certain borders. The infrastructure and staffing are already there, including ways to efficiently move traffic through. It's not feasible for other states to try to create and staff checkpoints like that on the fly.
Yes, as stated:the one state that is setup for this
one meaning that nobody else is setup for that.2 -
Just a PSA reminder that (just like with weight loss articles) just because a news or tabloid website posts an article and references a study, or even a statement by a scientific org, doesn't mean that the article is drawing the correct conclusion.
I just saw people on the tweeter loosing their crap because "eggs are bad again" because of some dumb self-reported correlation study that was inadequately reported on news sites. They are doing that with covid too, so if you don't feel like parsing the scientific language of the actual study, just keep distancing, wearing your mask(s), and looking for the darn vaccine and dont get lost in the weeds. The apocalypse has been stressful enough.
Exactly. I always sift through the article and find the actual study and look at it. I don't need a possibly dirty or twisted lens to look at it through TYVM. I can do it myself. I'm a big girl.
People on the tweeter (I will forever call it that now, so hilarious!) excel at losing their crap aren't they.4 -
baconslave wrote: »I couldn't find any information on this question but I'm curious, maybe someone here knows. Concerning receiving the Moderna vaccine, are recipients under age 55 known to have a tougher time with side effects than other age categories?
From what I have read it is more common of recipients under 55 to have a more robust response to vaccines. Vaccines have a substance called an "adjuvant" that is designed to alert the body that there is an invader to provoke a response. As older people have less energetic immune systems, their response is less pronounced. It just doesn't pounce as hard. The Covid vax acts the same. So I imagine that if that is the case for Modern, they used a more provocatory adjuvant. My Dad is 76, and he got severe aches and chills the night after the vaccine. And soreness at the injection site and that was all. He'll get his second tomorrow. So we shall see how he weathers that.
So the 2nd dose tends to overall provoke more severe reactions than the first across both, but according to this source, Moderna's overall side effects are worse than Pfizer's. https://www.healthline.com/health-news/heres-why-your-second-dose-of-covid-19-vaccine-will-likely-have-stronger-side-effects#Millions-of-doses,-few-problems
EDIT: Being the shameless nerd that I am, I couldn't let this go. According one study, neither use a separate adjuvant, but "BioNTech/Pfizer and Moderna do not explicitly state the use of an adjuvant within their vaccines, but RNA already contains immunostimulatory properties and signals through pathogen recognition receptors.72 It remains to be seen whether the immunostimulation from RNA is strong enough to confer full protection against SARS-CoV-2. There is also a possibility that the LNP carriers they utilize confer adjuvant properties themselves." Super neat. So if this is true, than the lipsomes and mRNA formulations in the Moderna are more naturally rowdy than the ones Pfizer uses.
(This source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553041/)
This exactly they talked about on TWIV. They supposed that older immune systems slowly react over time while younger immune systems just bang it right out. They also joked that older people might simply be more used to being tired and achy and don't notice it
My Dad has said that.
I need to add that podcast to my queue.2 -
https://bnonews.com/index.php/2021/02/russia-first-human-cases-of-h5n8-bird-flu/
Maybe thanks to Covid-19 learning experience over the last year things like h5n8 can be nipped in the bud to reduce the risk of another pandemic.2 -
https://www.mediaite.com/news/johns-hopkins-doctor-predicts-covid-will-be-mostly-gone-by-april/
Sounds like high rates of Covid-19 may be finally winding down the pandemic.2 -
GaleHawkins wrote: »https://www.mediaite.com/news/johns-hopkins-doctor-predicts-covid-will-be-mostly-gone-by-april/
Sounds like high rates of Covid-19 may be finally winding down the pandemic.
He is a surgeon, and that is not an opinion held by public health experts and virologists. Those people are hopeful that we will not see another large spike though, as hopefully vaccination rates will hold down hospitalizations going forward. I will continue to mask and distance until I get vaxxed, probably late summer, based on what they are saying.7 -
baconslave wrote: »baconslave wrote: »I couldn't find any information on this question but I'm curious, maybe someone here knows. Concerning receiving the Moderna vaccine, are recipients under age 55 known to have a tougher time with side effects than other age categories?
From what I have read it is more common of recipients under 55 to have a more robust response to vaccines. Vaccines have a substance called an "adjuvant" that is designed to alert the body that there is an invader to provoke a response. As older people have less energetic immune systems, their response is less pronounced. It just doesn't pounce as hard. The Covid vax acts the same. So I imagine that if that is the case for Modern, they used a more provocatory adjuvant. My Dad is 76, and he got severe aches and chills the night after the vaccine. And soreness at the injection site and that was all. He'll get his second tomorrow. So we shall see how he weathers that.
So the 2nd dose tends to overall provoke more severe reactions than the first across both, but according to this source, Moderna's overall side effects are worse than Pfizer's. https://www.healthline.com/health-news/heres-why-your-second-dose-of-covid-19-vaccine-will-likely-have-stronger-side-effects#Millions-of-doses,-few-problems
EDIT: Being the shameless nerd that I am, I couldn't let this go. According one study, neither use a separate adjuvant, but "BioNTech/Pfizer and Moderna do not explicitly state the use of an adjuvant within their vaccines, but RNA already contains immunostimulatory properties and signals through pathogen recognition receptors.72 It remains to be seen whether the immunostimulation from RNA is strong enough to confer full protection against SARS-CoV-2. There is also a possibility that the LNP carriers they utilize confer adjuvant properties themselves." Super neat. So if this is true, than the lipsomes and mRNA formulations in the Moderna are more naturally rowdy than the ones Pfizer uses.
(This source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553041/)
This exactly they talked about on TWIV. They supposed that older immune systems slowly react over time while younger immune systems just bang it right out. They also joked that older people might simply be more used to being tired and achy and don't notice it
My Dad has said that.
I need to add that podcast to my queue.
It can be dense, prob two thirds of it goes over my head lol but it's so reassuring. When they get really technical, I kind of zone out and drift back when it starts to sound like it's back on my level3 -
SuzySunshine99 wrote: »paperpudding wrote: »paperpudding wrote: »Yes being an island helps.
But UK is an island too - and nobody would be pleased with the covid situation there.
Low population density helps too and I'm sure all countries, just like here, have worse outbreaks in cities.
But border closures weren't just international - state borders closing was also crucial in containment.
Being an island simply helps you restrict travel, something AUS, NZ, Taiwan, etc did to contain the spread. As I recall, the UK felt it was inconvenient.
I think the conclusion of last year will be that lock downs without also restricting travel doesn't work.
It helps you cut international travel but Internal or state borders closing isnt an issue of being an island or not.
Yes I agree lockdowns and travel restrictions were both crucial.
You have mentioned the interstate travel restrictions. How did this work in Australia? Was it the "honor system", just essentially asking people not to cross state borders, or were there actual checkpoints set up?
I ask because it simply wouldn't be feasible in the U.S. to close state borders. There are no real border crossings, just tourism signs that say "Welcome to Iowa" or wherever. As an example, my state, Illinois, borders 5 other states. For just one of those borders, there are 83 roads that cross from Illinois into Wisconsin (I looked at a map and counted). Most people cross that border using two interstate highways, but there's no way you could stop traffic on a 8-lane interstate to check IDs. It's just not possible.
With 48 states that share borders with other states, it's not even a serious topic of discussion from a logistical sense.
People had to (and still do for some states) apply to cross the state borders g2g passes (good to go) or travel e passes depending on the risk level of where they have been or lived. Some states had hard borders on the roads to prevent people entering (eg Queensland, WA and SA). Can only enter Tasmania by air or Sea so that was more easily managed. No doubt some people likely breached the road borders (there were many news stories of those caught) and got away with with it but for the most part people did stay home during the worse for Australia.7 -
yes I concur with what tip toe said - for the large part, people complied anyway (there were exceptions eg for essential workers and compassionate reasons - those people applied for exemption passes) and many border cross points are highways which were manned and enforced.
Yes there were reports of people sneaking across via unsealed dirt roads - some whom got bogged and had to be rescued - needless to say, law took a dim view of such.
As almost everyone wanted to protect their state, not complying, as well as being illegal and making one subject to fines, also was unpopular and almost pointless - why would you want to sneak across when nobody would be happy to see you anyway and you would become a social pariah?9 -
baconslave wrote: »baconslave wrote: »I couldn't find any information on this question but I'm curious, maybe someone here knows. Concerning receiving the Moderna vaccine, are recipients under age 55 known to have a tougher time with side effects than other age categories?
From what I have read it is more common of recipients under 55 to have a more robust response to vaccines. Vaccines have a substance called an "adjuvant" that is designed to alert the body that there is an invader to provoke a response. As older people have less energetic immune systems, their response is less pronounced. It just doesn't pounce as hard. The Covid vax acts the same. So I imagine that if that is the case for Modern, they used a more provocatory adjuvant. My Dad is 76, and he got severe aches and chills the night after the vaccine. And soreness at the injection site and that was all. He'll get his second tomorrow. So we shall see how he weathers that.
So the 2nd dose tends to overall provoke more severe reactions than the first across both, but according to this source, Moderna's overall side effects are worse than Pfizer's. https://www.healthline.com/health-news/heres-why-your-second-dose-of-covid-19-vaccine-will-likely-have-stronger-side-effects#Millions-of-doses,-few-problems
EDIT: Being the shameless nerd that I am, I couldn't let this go. According one study, neither use a separate adjuvant, but "BioNTech/Pfizer and Moderna do not explicitly state the use of an adjuvant within their vaccines, but RNA already contains immunostimulatory properties and signals through pathogen recognition receptors.72 It remains to be seen whether the immunostimulation from RNA is strong enough to confer full protection against SARS-CoV-2. There is also a possibility that the LNP carriers they utilize confer adjuvant properties themselves." Super neat. So if this is true, than the lipsomes and mRNA formulations in the Moderna are more naturally rowdy than the ones Pfizer uses.
(This source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553041/)
This exactly they talked about on TWIV. They supposed that older immune systems slowly react over time while younger immune systems just bang it right out. They also joked that older people might simply be more used to being tired and achy and don't notice it
My Dad has said that.
I need to add that podcast to my queue.
It can be dense, prob two thirds of it goes over my head lol but it's so reassuring. When they get really technical, I kind of zone out and drift back when it starts to sound like it's back on my level
That sounds like my life as a technical recruiter for 25 years!
My brother has continued to improve, so that's been a huge relief. Getting ready soon for a road trip to TX, to move my daughter from Austin to here with us. She still has her car there and we have to sell most of her furniture. She's going to stay with us for a longer term and save money again -- most of her savings are gone after a year with Covid-19. Bittersweet to have her here. She was doing really well pre-Covid. A once, very happy and productive young professional woman is now very depressed and unsure of herself. It's been devistating, as a parent, to watch. I'm sure we're not unique in this whole pandemic.
We are just keeping our fingers crossed that her last month of utility bills won't be an incredibly horrible surprise. Not much choice on this trip. We will likely have to spend one day in a hotel (not thrilled about that) each way. I'll likely wear a mask nearly the entire time in the hotel.20 -
My daughter is having issues with anxiety and depression too. It’s kind of covid related. She’s been working from home for 4 years now, but she misses the social aspect of her life. Financially, she’s doing well, as she’s very frugal, but, she’s lonely. As an only child, she worries (she’s always been a worrier) about her elderly parents (late 60’s). At her regular doctors appointment last fall, they prescribed Prozac. They had to play around with dosage for a while, but she’s doing well now. Pre-covid, she traveled a lot, both for work and pleasure, so the past year no travel. There’s a tentative marathon scheduled in Kansas City in April, that a friend asked her to come along for support. She asked me to cat sit for her. I have mixed feelings. I’m glad to stay with her cat, but worried about the safety aspect.13
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